CS-0089777; (E)-3-[6-[1-(2-Chloro-6-Cyclopropylphenyl)Ethoxy]-4-Cyclopropylquinolin-3-yl]prop-2-Enoic acid; 2-Propenoic acid, 3-[6-[1-(2-Chloro-6-Cyclopropylphenyl)Ethoxy]-4-Cyclopropyl-3-Quinolinyl]-; HY-125176

Brief Introduction

G907 is a selective small-molecule antagonist of ATP-binding cassette (ABC) transporter, MsbA. It inhibits purified E. coli MsbA in amphipols with an IC50 of 18 nM. G907 traps MsbA in an inward-facing

SCY-078

CAS:1207753-03-4

Molecular Formula:C44H67N5O4

Alias

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MK 3118; MK-3118; SCY 078; (1S,4aR,6aS,7R,8R,10aR,10bR,12aR,14R,15R)-15-[[(2R)-2-Amino-2,3,3-Trimethylbutyl]oxy]-8-[(1R)-1,2-Dimethylpropyl]-14-[5-(4-Pyridinyl)-1H-1,2,4-Triazol-1-yl]-1,6,6a,7,8,9,10,10a,10b,11,12,12a-Dodecahydro-1,6a,8,10a-Tetramethyl-4H-1,4a-Propano-2H-Phenanthro[1,2-c]Pyran-7-Carboxylic acid; Ibrexafungerp; Ibrexafungerp(SCY-078)

Brief Introduction

Antifungal (SCY-078), a novel oral and intravenous (IV) drug for the treatment of severe and life-threatening invasive fungal infections in humans.

Trilaciclib

CAS:1374743-00-6

Molecular Formula:C24H30N8O

Alias

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2'-((5-(4-Methylpiperazin-1-yl)Pyridin-2-yl)Amino)-7',8'-Dihydro-6'H-Spiro(Cyclohexane-1,9'-Pyrazino(1',2':1,5)Pyrrolo(2,3-d)Pyrimidin)-6'-one; G1T28; G1T-28; 4-[[5-(4-Methylpiperazin-1-yl)Pyridin-2-yl]Amino]Spiro[1,3,5,11-Tetrazatricyclo[7.4.0.02,7]Trideca-2,4,6,8-Tetraene-13,1'-Cyclohexane]-10-one

Brief Introduction

Trilaciclib (G1T28, G1T28-1) is a potent and selective reversible inhibitor of cyclin-dependent kinase 4 and 6 (CDK4/6). Trilaciclib inhibits CDK4/cyclin D1 and CDK6/cyclin D3 with IC50 values of 1 nM and 4 nM, respectively.

Bromazepam

CAS:1812-30-2

Molecular Formula:C14H10BrN3O

Alias

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Bromaz; 7-Bromo-1,3-Dihydro-5-(2-Pyridyl)-2H-1,4-Benzodiazepin-2-one; 7-Bromo-5-Pyridin-2-yl-1,3-Dihydro-1,4-Benzodiazepin-2-one; Compedium; Durazanil; Lexotanil; Creosedin; Ultramidol; Lexilium

Brief Introduction

Controlled substance (depressant). Anxiolytic.

D13-9001

CAS:957471-96-4

Molecular Formula:C31H39N11O6S

Brief Introduction

D13-9001 is a potent AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor with the KD values of 1.15 μM and 3.57 μM in E. coli and P. aeruginosa, respectively. D13-9001 exhibits antibiotic activities.

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