Hormones and Endocrine Drugs

Dexamethasone is a synthetic corticosteroid that can be used to treat multiple symptoms, including rheumatic diseases, certain skin diseases, severe allergies, asthma, chronic obstructive pulmonary disease, hypersensitivity laryngitis, brain edema, and may be used in combination with antibiotics for tuberculosis patients. For patients with adrenal insufficiency, they should take drugs with corticosteroid, such as energetic ingots, etc. Dexamethasone can improve prognosis in preterm infants. The product usually starts to play its effect within one day, and the effect can be maintained for about three days. Long term use of dexamethasone can lead to candidiasis, bone loss, cataract, easy to stasis, or muscle fatigue. The pregnancy grade of this product in the United States is grade C, and the effect of the drug use should be evaluated to be greater than that of the side effects; Australia was rated a, indicating that the product is commonly used in pregnant women and there is no evidence that it will cause harm to the fetus. This medicine is not allowed during lactation. This product has the effect of anti-inflammatory and immunosuppression. Dexamethasone was first synthesized in 1957 and is listed in the list of who basic drugs standards, which is one of the essential drugs for basic public health system. The product is cheap and usually costs less than $25 a month in the United States. In India, preterm treatment costs only $0.5 a time. Dexamethasone is easily available in most countries.

Dehydroepiandrosterone (DHEA), chemical name is 3 – β– Hydroxyandrosterol – 5 – ene – 17 – one is a kind of cholesterol retaining △ 5,6 double bond and esterifiable 3 – β– The hydroxyl steroid has a molecular formula of C19H28O2, a molecular weight of 288.41, a melting point of 151 to 153 degrees centigrade, and an optical rotation of +5.5 degrees. It is an precursor of adrenal gland hormone secreted by the adrenal cortex reticular layer of the human body. It has the physiological functions of regulating obesity, preventing diabetes, resisting cancer and virus infection, improving memory, immune reaction and stress reaction, and reducing tension. It is an intermediate for the manufacture of steroid hormones and participates in the synthesis of adrenal glands to secrete a variety of hormones.

This product is prostaglandin F2 α The 15 methyl analogue can effectively promote the regular contraction of uterus and significantly reduce the amount of postpartum hemorrhage.

Used as a progesterone

Desonide is a glucocorticoid drug with anti-inflammatory, anti allergic, antipruritic and reducing exudation effects; It can reduce and prevent the reaction of tissue to inflammation, eliminate the fever, redness and swelling caused by local non infectious inflammation, so as to reduce the performance of inflammation; It has the immunosuppressive effect of preventing or inhibiting cellular immune response and inhibiting primary immune response.