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Hormones and Endocrine Drugs

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CAS:149709-62-6
Molecular Formula:C24H29NO5
Entresto (Trade Name, With Valsartan Sodium); 4-[[(2S,4R)-5-Ethoxy-4-Methyl-5-Oxo-1-(4-Phenylphenyl)Pentan-2-Yl]Amino]-4-Oxobutanoic Acid; Ahu-377; 4-(((2S,4R)-1-([1,1'-Biphenyl]-4-Yl)-5-Ethoxy-4-Methyl-5-Oxopentan-2-Yl)Amino)-4-Oxobutanoic Acid; 4-(((2R,4R)-1-([1,1'-Biphenyl]-4-Yl)-5-Ethoxy-4-Methyl-5-Oxopentan-2-Yl)Amino)-4-Oxobutanoic Acid; (2R,4S)-5-(Biphenyl-4-Yl)-4-[(3-Carboxypropionyl)Amino]-2-Methylpentanoic Acid Ethyl Ester; (2R,4S)-5-([1,1'-Biphenyl]-4-Yl)-4-(3-Carboxypropanamido)-2-Methylpentanoic Acid; Ahu-377,149709-62-6; Ahu-37; Ahu377; Ahu 377
Brief Introduction
Sacubitril (INN developmental code name AHU-377) is an antihypertensive drug used in combination with valsartan. The combination drug valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name Entresto, is a treatment for heart failure. It was approved under the FDA's priority review process for use in heart failure on July 7, 2015.
CAS:157283-68-6
Molecular Formula:C26H35F3O6
Fluprostenol Isopropyl Ester; Travatan; Travaprost; Flu-Ipr; (+)-9Alpha,11Alpha,15R-Trihydroxy-16-(3-(Trifluoromethyl)Phenoxy)-17,18,19,20-Tetranor-Prosta-5Z,13E-Dien-1-Oic Acid, Isopropyl Ester; (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-Hydroxy-4-[3-(Trifluoromethyl)Phenoxy]-1-Buten-1-Yl]Cyclopentyl]-5-Heptenoic Acid 1-Methyethyl Ester; (+/-)-16-(M-Trifluoromethylphenoxy)Tetranorprostaglandin F2; 15(S)-Flu-Ipr; 15(S)-Fluprostenol Isopropyl Ester; 5-Heptenoic Acid, 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-Hydroxy-4-[3-(Trifluoromethyl)Phenoxy]-1-Buten-1-Yl]Cyclopentyl]-, 1-Methylethyl Ester, (5Z)-; Propan-2-Yl (E)-7-[(1R,2S,3R,5S)-3,5-Dihydroxy-2-[(E)-3-Hydroxy-4-[3-(Trifluoromethyl)Phenoxy]But-1-Enyl]Cyclopentyl]Hept-5-Enoate; Trevostaglandin
Brief Introduction
It is used to reduce elevated intraocular pressure in patients with open-angle glaucoma or high intraocular pressure.
CAS:164656-23-9
Molecular Formula:C27H30F6N2O2
(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(Trifluoromethyl)Phenyl]-9a,11a-Dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-Dodecahydroindeno[5,4-f]Quinoline-1-Carboxamide; (5Alpha,17beta)-N-(2,5-Bis(Trifluoromethyl)Phenyl)-3-oxo-4-Azaandrost-1-ene-17-Carboxamide; Alpha,Alpha,Alpha,Alpha',Alpha',Alpha'-Hexafluoro-3-oxo-4-aza-5Alpha-Androst-1-ene-17beta-Carboxy-2',5'-Xylidide; Avodart; Duagen
Brief Introduction
Dutasteride is a new 5 α Dual inhibitor of reductase, used in patients with moderate and severe symptoms of benign prostatic hyperplasia
CAS:183133-96-2
Molecular Formula:C45H57NO14
Jevtana; Cabazitaxelum; Jevtana Kit; Kabazitaxel; Cabazitaxel (Jevtana)
Brief Introduction
Carbataxel combined with prednisone is used to treat hormone refractory metastatic prostate cancer previously treated with docetaxel containing regimen.
CAS:21187-98-4
Molecular Formula:C15H21N3O3S
Glyzide; Diaprel; Diamicron; Glimicron; 1-[3-Azabicyclo[3.3.0]Oct-3-Yl]-3-P-Toluenesulfonylurea; 1-(3-Azabicyclo[3.3.0]Oct-3-Yl)-3-P-Tolylsulphonylurea; S-1702; Nordialex; S852; Glinormax; 1-(3-Azabicyclo(3.3.0)Oct-3-Yl)-3-(P-Tolylsulfonyl)Urea; 1-(Hexahydrocyclopenta(C)Pyrrol-2(1H)-Yl)-3-(P-Tolylsulfonyl)Urea; Benzenesulfonamide,N-(((Hexahydrocyclopenta(C)Pyrrol-2(1H)-Yl)Amino)Carbonyl; N-(4-Methylbenzenesulfonyl)-N'-(3-Azabicyclo(3.3.0)Oct-3-Yl)Urea; Tetrabenzyl Voglibose Hcl; Glicazeder
Brief Introduction
Gliclazide is the second generation of sulfonylurea oral hypoglycemic agents. It has both the hypoglycemic effect and the improvement of coagulation function. It can not only improve the metabolism of diabetic patients, but also improve or delay the occurrence of diabetic vascular complications. Developed by SERVIER, France, it was first listed in France in 1972. It is marketed as dacicam, methanesulfide, methanesulfide, bicyclic urea, Lai Keyi, methanesulfide and Glick NAC. It is mainly used for mild and medium II diabetes without onset of ketosis. It can also improve the fundus lesion and metabolism of diabetic patients. Vascular dysfunction. It can be combined with oral hypoglycemic agents of double guanidin and insulin in the treatment of insulin-dependent diabetes mellitus, which can reduce the dosage of insulin. It began to supply to China market in 1980s and has been registered and sold in more than 130 countries around the world.
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