Hormones and Endocrine Drugs

This product is a kind of glucocorticoid with anti-inflammatory, anti allergic, anti toxin and anti shock effects.

Prednisolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations.

Dexamethasone sodium phosphate belongs to adrenocortical hormone drugs, which can stabilize lysosomal membrane and reduce the release of lysosomal hydrolase; It can inhibit the production of bradykinin, 5-hydroxytryptamine and prostaglandin, increase the stability of mast cell granules and reduce the release of histamine; Constrict blood vessels, inhibit the migration of leukocytes and macrophages outside blood vessels, so as to have anti-inflammatory effect. It can exert immunosuppressive effect by inhibiting the function of macrophages. It can inhibit the formation of fibroblasts, prevent corneal scar, reduce scar formation and protect vision when used in trauma. It can inhibit or reduce the formation of neovascularization in corneal and conjunctival diseases. Local application can reduce rejection and scar formation in corneal transplantation and myopic surgery. It is clinically used for the treatment of autoimmune diseases, allergies, inflammation, rheumatism, asthma, ophthalmology and dermatology.

Dinogestrin is a newly listed selective luteal hormone drug in recent years. It can play a role in stabilizing endometrial tissue by specifically binding ethylene nortestosterone and progesterone derivatives. It has been found that tumor necrosis factor (TNF). And interleukin-8 (IL-8) increased in patients with endometriosis.

Medroxyprogesterone acetate can replace uterine curettage. After adjuvant anti infection treatment, it can reduce the complications of drug abortion, quickly reduce bleeding and stop bleeding as soon as possible. The clinical operation method is simple, the patient's compliance is good, easy to accept, and has good clinical feasibility; In addition, it can also be widely used in the treatment of irregular menstruation, dysmenorrhea and so on. Injections can be used as long-acting contraceptives, and large doses are used to treat breast cancer.