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Antineoplastic Agents

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CAS:936563-96-1
Molecular Formula:C25H24N6O2
Imbruvica
Brief Introduction
Ibrutinib is an oral small molecule targeted drug. It is the world's first Btk (Bruton tyrosine kinase) inhibitor. It can irreversibly bind to Btk protein and block its function, resulting in cancer cell death, tumor shrinkage and cancer remission
CAS:129453-61-8
Molecular Formula:C32H47F5O3S
Faslodex (Trade Name); (7R,8R,9S,13S,14S,17S)-13-Methyl-7-[9-(4,4,5,5,5-Pentafluoropentylsulfinyl)Nonyl]-6,7,8,9,11,12,14,15,16,17-Decahydrocyclopenta[A]Phenanthrene-3,17-Diol; (7A,17B)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)Sulfinyl]Nonyl]Estra-1,3,5(10)-Triene-3,17-Diol; 7A,17B-[9[(4,4,5,5,5-Pentafluoropentyl)Sulfinyl]Nonyl]Estra-1,3,5(10)-Triene-3,17-Diol; (7Alpha,17Beta)-Nonyl); Estra-1,3,5(10)-Triene-3,17-Diol,7-(9-((4,4,5,5,5-Pentafluoropentyl)Sulfinyl); 7-[9-[(4,4,5,5,5-Pentafluoropentyl)Sulfinyl]Nonyl]- (7α,17β)-Estra-1,3,5(10)-Triene-3,17-Diol
Brief Introduction
Fluticasone is an intramuscular injection developed by AstraZeneca. It was approved by the food and Drug Administration in April 2002 to treat estrogen receptor positive metastatic breast cancer in postmenopausal women whose disease is still deteriorating after anti estrogen therapy. Many breast cancer cells have estrogen receptor (ER), estrogen can stimulate the growth of such tumors. Fluvestrant is a "pure" estrogen receptor antagonist without partial estrogen like agonistic effect. It inhibits estrogen signal pathway by binding, blocking and down regulating er. It can competitively bind with ER. Its affinity with Er is close to estrogen, 100 times that of tamoxifen. It is the only anti estrogen drug that can be widely used in clinic after tamoxifen fails, Because the drug is endocrine therapy and will not cause common adverse reactions of chemotherapy, it has good patient compliance.
Mixed Tocopherols
Brief Introduction
Using mixed tocopherol concentrate as raw material, various specifications of mixed natural vitamin E are purified and compounded through chemical processes such as pretreatment, adsorption separation and molecular distillation.
CAS:66-22-8
Molecular Formula:C4H4N2O2
2,4-Dihydroxypyrimidine; 4-Hydroxy-2(1H)-Pyrimidinone; 4-Pyrimidinol; 4-Pyrimidone; 4H-Pyrimidin-2-one; Beta-Uracil; NSC 767; Uracil-4-ol; 2,4(1H,3H)-Pyrimidinedione; 2,4-Dioxo-3,4-Dihydropyrimidin; Urasil; 1H-Pyrimidine-2,4-Dione; 2,4-Pyrimidinediol
Brief Introduction
Uracil is an organic base, one of the four main bases in RNA, a major pyrimidine component in RNA, and also a component of various uridine acids. The triphosphate compound of uridine is urine triphosphate, which is the precursor of uracil in the process of ribonucleic acid biosynthesis. Urine triphosphate as coenzyme participates in the synthesis of some sugar biochemical books.
CAS:75607-67-9
Molecular Formula:C10H13FN5O7P
9-Beta-D-Arabinofuranosyl-2-Fluoroadenine5’-Monophosphate; Fludarabinemonophosphate; 9-Beta-D-Arabinofuranosyl-2-Fluoroadenine-5'-Dihydrogen Phosphate; Fludarabine(NSC-118218)Phosphate; 2-Fluoro-9-(5-o-Phosphono-beta-d-Arabinofuranosyl)-9h-Purin-6-Amine; 2-Fluoro-Araamp;9-beta-Arabinofuranosyl-2-Fluoroadchemicalbookenine-5’-Phosphate; 5-Monophosphate
Brief Introduction
It has a role as an antimetabolite, an antineoplastic agent, an immunosuppressive agent, an antiviral agent, a prodrug and a DNA synthesis inhibitor.
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