((2-(6-Amino-9H-Purin-9-Yl)Ethoxy)Methyl)Phosphonic Acid; Pmea; Treatment Adefovir; Tenofovir Desmethyl Impurity; 2-(6-Amino-9H-Purin-; Adefovir Dipivox (Pmea); [[2-(6-Amino-9H-Purin-9-Yl)Ethoxy]; Methyl]Phosponic Acid; P-[[2-(6-Amino-9H-Purin-9-Yl)Ethoxy]Methyl]Phosphonic Acid; Adefovir(Pmea)

Brief Introduction

Adefovir is a acyclic nucleoside analogue of adenosine monophosphate. It is a new type of anti HBV drug. It is used in the form of the former drug A Duff Vee ester, and belongs to adenine nucleoside. Under the action of cell kinase, Adefovir is phosphorylated to an active metabolite, namely adefovir diphosphate. Adefovir diphosphate inhibits HBV DNA polymerase (reverse transcriptase) in two ways. One is that it competes with the natural substrate deoxyadenosine triphosphate, and the other is that it causes DNA strand elongation and termination after integration into virus DNA. Therefore, Adefovir is mainly used for the treatment of adult chronic hepatitis B patients with evidence of active replication of hepatitis B virus, continuous increase of serum amino acid transferase (ATL or AST), or liver tissue active lesions with liver function compensation.

Perindopril Erbumine

CAS:107133-36-8

Molecular Formula:C23H43N3O5

Alias

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Aceon; Perindopril Tert-Butylamine; Prestarium; Perindopril T-Butylamine Salt; Unii-1964X464Oj; Butylaminiperindopril; Perinodopril; Coversum; Perindoril; Prindopril Api; (2S,3As,7As)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)Butyl]Amino]-1-Oxopropyl]Octahydro-1H-Indole-2-Carboxylic Acid Tert-Butylamine Salt; (2S,3As,7As)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)Butyl]Amino]-1-Oxopropyl]Octahydro-1H-Indole-2-Carboxylic Acid 2-Methyl-2-Propanamine

Brief Introduction

Perindopril is an inhibitor of an enzyme (angiotensin converting enzyme) that converts angiotensin I to angiotensin II. This kind of invertase or kinase is a kind of peptidolytic enzyme. It can convert angiotensin I into angiotensin II, which is used to constrict blood vessels. It can also degrade bradykinin, which is used to dilate blood vessels, into inactive heptapeptide. Inhibition of angiotensin converting enzyme results in a decrease of angiotensin II in plasma, which leads to an increase in plasma renin activity (by inhibiting the negative feedback of renin release) and a decrease in aldosterone secretion. Because angiotensin-converting enzyme inactivates bradykinin, inhibition of angiotensin-converting enzyme can also increase the activity of circulating and local kallikrein kinin system (and thus prostaglandin system). This mechanism may be related to the effect of angiotensin converting enzyme inhibitors on lowering blood pressure, and may also be related to some side effects (such as cough). Perindopril acts through its active metabolite perindoprila.

Cefeprime Dihydrochloride

CAS:107648-80-6

Molecular Formula:C19H26Cl2N6O5S2

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Pyrrolidinium,1-[[(6R,7R)-7-[[(2Z)-2-(2-Amino-4-Thiazolyl)-2-(Methoxyimino)Acetyl]Amino]-2-Carboxy-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-En-3-Yl]Methyl]-1-Methyl-,Chloride,Hydrochloride (1:1:1; 1-[[(6R,7R)-7-[2-(2-Amino-4-Thiazolyl)-2-(Z-Methoxyimino)-Acetamido]-2-Carboxy-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-En-3-Yl]Methyl]-1-Methyl-Pyrrolidinium Chloride,Monohydrochloride; L-[[(6R,7R)-7-[2-(2-Amino-4-Thiazolyl)-Glyoxylamido]-2-Carboxy-8-Oxo-5-Thia-L-Azabicyclo[4.2.0]Oct-2-En-3-Yl]Methyl]-1-Methyl-Pyrrolidinium Chloride; 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-Thiazolyl)(Methoxyimino)Acetyl]Amino]-2-Carboxy-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-En-3-Yl]Methyl]-1-Methyl-Pyrrolidinium Chloride Hydrochloride; Cefepime Dihydrochloride; (6R,7R)-7-[[(2E)-2-(2-Amino-1,3-Thiazol-4-Yl)-2-Methoxyiminoacetyl]Amino]-3-[(1-Methylpyrrolidin-1-Ium-1-Yl)Methyl]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid Chloride Hydrochloride; Cefepime Hcl Sterile Powder; Cefepime Hcl; Cefepime Hydrochloric; Pyrrolidinium,1-[[(6R,7R)-7-[[(2Z)-2-(2-Amino-4-Thiazolyl)-2-(Me

Brief Introduction

For the treatment of a variety of bacterial infections, including severe infections.

2-((1-(1-(4-Fluorobenzyl)-1H-Benzo[D]Imidazol-2-Yl)Piperidin-4-Yl)(Methyl)Amino)Pyrimidin-4(1H)-One

CAS:108612-45-9

Molecular Formula:C24H25FN6O

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Mizolastine; Mizollen; Zolistan; Sl 85.0324

Brief Introduction

Mizolastine is an antihistamine, also known as mizolastine. It not only has strong antihistamine effect, but also can inhibit other inflammatory transmitters, such as inhibiting the production of leukotrienes and reducing edema. Therefore, in theory, mizolastine not only has antihistamine and antiallergic effects, but also has anti-inflammatory activity. It is the preferred drug for the treatment of acute urticaria. It takes effect significantly faster than other antihistamines. After 1 ~ 3 hours, the number of wind masses is reduced, the degree of pruritus is reduced, and the maintenance time is long, up to 24 hours. At present, it is mainly used to treat skin allergy symptoms such as urticaria, seasonal allergic rhinitis (hay fever) and perennial allergic rhinitis in adults or children over 12 years old.

1H-Pyrrole

CAS:109-97-7

Molecular Formula:C4H5N

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Monopyrrole; Parzate; Divinylenimine; Pyrroline; 1H-Pyrrole; Pyrrol; Fema 3386; Pyrrole; Pyrrhol; Azole; Azole,Divinylenimine,Imidole; Imidole

Brief Introduction

Pyrrole and its homologues are mainly found in bone tar, but few in coal tar. Pyrrole can be obtained by fractionation of bone tar; Or it can be treated with dilute alkali and then purified by fractionation after acidification. It is a five membered heterocyclic compound with one aza atom and its molecular formula is C4H5N. It is also used in organic synthesis and pharmaceutical industry. Mainly used as polyester fiber spinning solvent. It is also used as metal preservative, curing agent of epoxy resin, catalyst for olefin polymerization and raw material for pharmaceutical industry. It is also used as a photosensitizer.

1
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82
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84
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256

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