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CAS:102082-89-3
Molecular Formula:C9H6F2O2
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Trans-2,6-Difluorociamic Acid; Trans-3-(2,6-Difluorophenyl)Acrylic Acid; Trans-2,6-Difluorocinnamicacid; (2E)-3-(2,6-Difluorophenyl)-2-Propenoic Acid; 3-(2,6-Difluoro-Phenyl)-Acrylic Acid
Brief Introduction
This product can be used as pharmaceutical raw materials for organic synthesis.
CAS:103060-53-3
Molecular Formula:C72H101N17O26
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Cubicin; Daptomycin,N-(1-Oxodecyl)-L-Tryptophyl-D-Asparaginyl-L-α-Aspartyl-L-Threonylglycyl-L-Ornithinyl-L-α-Aspartyl-D-Alanyl-L-α-Aspartylglycyl-D-Seryl-(3R)-3-Methyl-L-α-Glutamyl-α,2-Diamino-γ-Oxo-Benzenebutanoicacid(13-4)Lactone; Cubicin Daptomycin; Cidecin; N-[N-(1-Oxodecyl)-L-Trp-D-Asn-L-Asp-]-Cyclo[L-Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-Methyl-L-Glu-]-4-(2-Aminophenyl)-4-Oxo-L-Abu-]; N-[N-Decanoyl-L-Trp-D-Asn-L-Asp-]-Cyclo[Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-Methyl-L-Glu-]-3-(2-Aminobenzoyl)-L-Ala-]; N-(1-Oxodecyl)-L-Tryptophyl-D-Asparaginyl-L-α-Aspartyl-L-Threonylglycyl-L-Ornithinyl-L-α-Aspartyl-D-Alanyl-L-α-Aspartylglycyl-D-Seryl-(3R)-3-Methyl-L-α-Glutamyl-α,2-Diamino-γ-Oxo-Benzenebutanoicacid(13-4)Lactone; Daptomycine; Dapcin
Brief Introduction
Daptomycin is a new cyclic lipopeptide antibiotic extracted from the fermentation broth of Streptomyces (S. reesosporus). It was discovered by Eli Lilly in the 1980s and successfully developed by Cubist pharmaceutical company in 1997. It not only has a novel chemical structure, but also can be used in the production of daptomycin, Moreover, its mode of action is different from any approved antibiotic: it can disrupt the transport of amino acids in the cell membrane, thus hindering the biosynthesis of peptidoglycan in the bacterial cell wall, changing the properties of the cell plasma membrane, destroying the function of the bacterial cell membrane in many aspects, and rapidly killing Gram-positive bacteria. In addition to acting on most clinical related Gram-positive bacteria, daptomycin is more important for its strong activity in vitro against isolated strains with resistance to methicillin, vancomycin and linezolid, which is of great clinical significance for critically ill patients with infection.
CAS:10361-46-3
Molecular Formula:Bi5H9N4O22
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Bismuth Subnitrate; Bismuth Nitrate Oxide; Oxobismuthanyl Nitrate
Brief Introduction
It is used to test sugars and alkaloids in clinical tests. Manufacturing bismuth salt and ceramic glaze. Medically, it is a medicine for neutralizing gastric acid and astringent. It is used for gastric and duodenal ulcer and diarrhea
CAS:104987-11-3
Molecular Formula:C44H69NO12
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Fujimycin; Prograf; Protopic; Fk506; Tacrolimus Anhydrous; Advagraf; Modigraf; Protopy; Anhydrous Tacrolimus; 8-Deethyl-8-[But-3-Enyl]-Ascomycin; Unii-Y5L2157C4J; (-)-Fk 506; Tsukubaenolide; Prograf (Tn); Prograft; Avagraf; Envarsus; Graceptor; Envarsus Xr; (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26As)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26A-Hexadecahydro-5,19-Dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-Hydroxy-3-Methoxycyclohexyl]-1-Methylethenyl]-14,16-Dimethoxy-4,10,12,18-Tetramethyl-8-(2-Propen-1-Yl)-15,19-Epoxy-3H-Pyrido[2,1-C][1,4]Oxaazacyclotricosine-1,7,20,21(4H,23H)Tetrone
Brief Introduction
Tacrolimus is a macrolide drug isolated from Streptomyces, which has strong immunosuppressive effect. Tacrolimus can specifically bind and inhibit calmodulin phosphatase activity, inhibit IL-2 signal transcription, thus inhibit T cell activation and TNF- α、 IL-1 β And IL-6 production and T cell dependent B cell proliferation. Compared with cyclosporine, another calmodulin phosphatase inhibitor, tacrolimus has stronger inhibitory effect on T cell activation and less adverse reactions.
CAS:106941-25-7
Molecular Formula:C8H12N5O4P
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((2-(6-Amino-9H-Purin-9-Yl)Ethoxy)Methyl)Phosphonic Acid; Pmea; Treatment Adefovir; Tenofovir Desmethyl Impurity; 2-(6-Amino-9H-Purin-; Adefovir Dipivox (Pmea); [[2-(6-Amino-9H-Purin-9-Yl)Ethoxy]; Methyl]Phosponic Acid; P-[[2-(6-Amino-9H-Purin-9-Yl)Ethoxy]Methyl]Phosphonic Acid; Adefovir(Pmea)
Brief Introduction
Adefovir is a acyclic nucleoside analogue of adenosine monophosphate. It is a new type of anti HBV drug. It is used in the form of the former drug A Duff Vee ester, and belongs to adenine nucleoside. Under the action of cell kinase, Adefovir is phosphorylated to an active metabolite, namely adefovir diphosphate. Adefovir diphosphate inhibits HBV DNA polymerase (reverse transcriptase) in two ways. One is that it competes with the natural substrate deoxyadenosine triphosphate, and the other is that it causes DNA strand elongation and termination after integration into virus DNA. Therefore, Adefovir is mainly used for the treatment of adult chronic hepatitis B patients with evidence of active replication of hepatitis B virus, continuous increase of serum amino acid transferase (ATL or AST), or liver tissue active lesions with liver function compensation.
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