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CAS:16773-42-5
Molecular Formula:C7H10ClN3O3
1-(3-Chloro-2-Hydroxypropyl)-2-Methyl-5-Nitroimidazole; 1-Chloro-3-(2-Methyl-5-Nitro-1H-Imidazol-1-Yl)-2-Propanol; 1-Chloro-3-(2-Methyl-5-Nitro-1H-Imidazol-1-Yl)Propan-2-Ol; 1-Chloro-3-(2-Methyl-5-Nitroimidazol-1-Yl)Propan-2-Ol; Ornidazol A-(Chloromethyl)-2-Methyl-5-Nitro-1H-Imidazole-1-Ethanol; Alpha-(Chlormethyl)-2-Methyl-5-Nitro-Imidazol-1-Aethanol; Alpha-(Chloromethyl)-2-Methyl-5-Nitro-1H-Imidazole-1-Ethano; Ro7-0207
Brief Introduction
Ornidazole is the third generation of nitroimidazole, which has obvious antibacterial advantages over metronidazole and Tinidazole. The half-life of plasma elimination of ornidazole is 14.4 hours, which is higher than that of metronidazole (8.4 hours) and Tinidazole (12.7 hours). Therefore, ornidazole can reduce the times of taking medicine and is more convenient to use. It acts on the DNA of anaerobes, amoebas, Giardia and Trichomonas cells to break their helix structure or prevent their transcription and replication, resulting in the death of pathogenic bacteria. The peak plasma concentration was reached 2 hours after oral administration, and the bioavailability was about 90%.
Brief Introduction
Vofopitant (GR-205,171) is a drug which acts as an NK1 receptor antagonist. It has antiemetic effects as with other NK1 antagonists, and also shows anxiolytic actions in animals. It was trialled for applications such as the treatment of social phobia and post-traumatic stress disorder, but did not prove sufficiently effective to be marketed.
CAS:1685-80-9
Molecular Formula:C11H12O2
(2E)-3-(2,4-Dimethylphenyl)Acrylic Acid; 3-(2,4-Dimethylphenyl)Acrylic Acid; (E)-3-(2,4-Dimethylphenyl)Prop-2-Enoic Acid; 3-(2,4-Dimethylphenyl)Prop-2-Enoic Acid; 2-Propenoic Acid, 3-(2,4-Dimethylphenyl)-
Brief Introduction
This product is an organic synthetic intermediate and can be used as a pharmaceutical intermediate.
CAS:16909-11-8
Molecular Formula:C11H12O4
Imethoxycinnamic Acid; 3-(3,5-Dimethoxyphenyl)Acrylic Acid; 3,5-Dimethoxy Cinnamic Acid; 3-(3,5-Dimethoxyphenyl)Propenoic Acid
Brief Introduction
This product is an organic acid, which can be used as pharmaceutical raw materials and intermediates.
CAS:16985-03-8
Molecular Formula:C25H33NO2
2-Methyl-4-<Pyridyl-(4)>-5-Hydroxy-6-<3-Methyloctyl-(2)>-2H-Chromenyl-(2)-Oxymagnesiumbromid; Nonabino; 2,2-Dimethyl-7-(3-Methyloctan-2-Yl)-4-(Pyridin-4-Yl)-2H-Chromen-5-Ol; 7-(1,2-Dimethyl-Heptyl)-2,2-Dimethyl-4-Pyridin-4-Yl-2H-Chromen-5-Ol; Nonabinum [Inn-Latin]; 2,2-Dimethyl-7-(3-Methyl-2-Octyl)-4-(4-Pyridyl)-2H-Chromen-5-Ol; 2,2-Dimethyl-5-Hydroxy-7-(3-Methyl-2-Octyl)-4-(4-Pyridyl)-2H-1-Benzopyran; Nonabine; Nonabinum; Nonabino [Inn-Spanish]; Unii-77Duk856J7; Brl-4664; 77Duk856J7
Brief Introduction
Nonabine (BRL-4664) is a drug which is a cannabinoid derivative, which was developed for the prevention of nausea and vomiting associated with cancer chemotherapy. It has strong antiemetic effects equivalent to those of chlorpromazine, and also produces some mild sedative effects, along with dry mouth and EEG changes typical of cannabinoid agonists, but with minimal changes in mood or perception, suggesting the abuse potential is likely to be low.
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