Pharmaceutical Intermediates

It is the intermediate of yantongjing, telden, chlorpromazine, imipramine, doxepin and amitriptyline.

Ethyl chloroformate is mainly used as an intermediate in organic synthesis to produce diethyl formate, isocyanate, medicine, pesticide, herbicide and flotation agent, and also as a solvent. At present, the most important use of ethyl chloroformate is as an intermediate of herbicide cyclohexanone.

1,3-Dichlorobenzene is an organic compound with the formula C6H4Cl2. It is the least common of the three isomers of dichlorobenzene, it is a colorless liquid that is insoluble in water. It is produced as a minor byproduct of the chlorination of benzene, but can also be prepared in a directed manner by the Sandmeyer reaction of 3-chloroaniline. It also arises from the isomerization of the other dichlorobenzenes at high temperature.Used in organic synthesis. The Friedel-Crafts reaction between m-dichlorobenzene and chloroacetyl chloride yields 2,4,ω-trichloroacetophenone, which is used as an intermediate for the broad-spectrum antifungal drug miconazole. The chlorination reaction is carried out in the presence of ferric chloride or aluminum mercury, and 1,2,4-trichlorobenzene is mainly produced. In the presence of a catalyst, it is hydrolyzed at 550-850°C to produce m-chlorophenol and resorcinol. Using copper oxide as a catalyst, it reacts with concentrated ammonia at 150-200°C under pressure to generate m-phenylenediamine. 2. Used in dye manufacturing, organic synthesis intermediates and solvents.

Hydroxylamine hydrochloride is white acicular crystal, easy to deliquescence, soluble in water, ethanol and glycerol, insoluble in ether. Hydroxylamine hydrochloride is an important organic chemical intermediate, which is mainly used in the preparation of oxime in organic synthesis, such as the intermediate of sulfamethoxazole in pharmaceutical industry and the intermediate of indigo in synthetic dye industry. As hydroxylamine hydrochloride has good reducing effect, it is often used as reducing agent in industry, such as antioxidant and antioxidant of fatty acid and soap in oil industry.

This product can be used to manufacture a variety of pesticides, fungicides and herbicides. It is an important intermediate of medicine and pesticides.