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Synthetic Anti Infective Drugs

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CAS:2022-85-7
Molecular Formula:C4H4FN3O
5-Fluorocytosine; 4-Amino-5-Fluoro-2(1H)-Pyrimidinone,5-Fluorocytosine,Flucytosine; 4-Amino-5-Fluoro-1,2-Dihydropyrimidin-2-One; 4-Amino-5-Fluoro-2(1H)-Pyrimidinone,Flucytosine; 4-Amino-5-Fluoro-2-Pyrimidone; Fluocytosine; Ancotil; 5-Fluorocytosin; Fluorcytosine; 6-Amino-5-Fluoro-1H-Pyrimidin-2-One; Flucytosin; 5-Fluorocystosine; 4-Amino-5-Fluoro-2-Hydroxypyrimidine; 4-Amino-5-Fluoro-2(1H)-Pyrimidinone; Ancobon; Fluorocytosine
Brief Introduction
5-fluorocytosine (5-FC), also known as 5-fluorocytosine, 5-fluorocytidine, anjezhi, and anlapen, is a white or quasi white crystalline powder. The inhibitory effect of 5-fluorocytosine on fungi is due to its entering into the cells of sensitive fungi, and under the action of cytosine deaminase, 5-fluorouracil, an anti metabolite, is formed. The latter is converted to 5-fluorouracil-2-deoxyriboside, which inhibits thymidine synthase, blocks the conversion of 5-fluorouracil-2-deoxyriboside to thymidine, and affects DNA synthesis. It has a good inhibitory effect on Candida, Cryptococcus and hyphomycetes, and also has an effect on some Aspergillus, as well as mycospores and bottle fungi which cause skin fungal diseases.
CAS:5508-58-7
Molecular Formula:C20H30O5
Andrographis; Rhizoma Sparganii; Andrographolid; Andrographis Paniculata(Burm.f) Nees; Andro; Andrographalide; Ent-(3β,12E,14R)-3,14,19-Trihydroxy-8(17),12-Labdadien-16,15-Olide; Andrographolide/Andrographis Paniculata P.E.; 5-Alpha,6-Alpha,8A-Alpha))-T; 2(3H)-Furanone,3-(2-(Decahydro-6-Hydroxy-5-(Hydroxymethyl)-5,8A-Dimethyl-2-Met; 3-(2-(Decahydro-6-Hydroxy-5-(Hydroxymethyl)-5,8A-Dimethyl-2-Methylene- 1-Naphthalenyl)Ethylidene)Dihydro-4-Hydroxy-, (1R-(1-Alpha(E(S*)),4A-Beta,5- Alpha,6-Alpha,8A-Alpha))-2(3H)-Furanone; (3E,4S)-3-[2-[(1R,4As,5R,6R,8As)-1,2,3,4,4A,5,6,7,8,8A-Decahydro-6-Hydroxy-5-(Hydroxymethyl)-5,8A-Dimethyl-2-Methylenenaphthalene-1-Yl]Ethylidene]Dihydro-4-Hydroxy-2(3H)-Furanone; (S)-3-[(E)-2-[[(1R,4Aα)-Decahydro-6β-Hydroxy-5β-Hydroxymethyl-5,8Aβ-Dimethyl-2-Methylenenaphthalen]-1β-Yl]Ethylidene]Dihydro-4-Hydroxy-2(3H)-Furanone
Brief Introduction
Andrographolide is a labdane diterpenoid that has been isolated from the stem and leaves of Andrographis paniculata. Andrographolide is an extremely bitter substance. Andrographolide has been studied for its effects on cell signaling, immunomodulation, and stroke. Study has shown that andrographlide may bind to a spectrum of protein targets including NF-κB and actin by covalent modification.
CAS:25655-41-8
Molecular Formula:C8H15NO
Povidoneiodine; PVP-Iodine Complex; Iodine-Polyvinylpyrrolidonecomplex; Poly(1-(2-Oxo-1-Pyrrolidinyl)Ethylene)Iodinecomplex; Betadine; Pvp-Iodine; Povidone-Iodine; Iodinatedpovidone; Povidonum Iodinatum Comples of Polyvinyl Pyrrolidone and Iodine; PVP-I; 25655_41-8
Brief Introduction
Skin disinfection and instrument disinfection for hospital operation and injection, infection prevention for Stomatology, gynecology, surgery and dermatology, sterilization and disinfection for household tableware and instruments, sterilization and disinfection for food industry and breeding industry, prevention and treatment of animal diseases, etc. It is the first choice of iodine containing medical bactericide and sanitary and epidemic prevention disinfectant in developed countries. Povidone iodine has excellent sterilization and disinfection ability and physiological compatibility, which shows that povidone iodine has no irritation and allergic reaction to human body, so povidone iodine is also widely used in food preservation, catering disinfection and so on.
CAS:1985606-14-1
Molecular Formula:C27H23F2N3O7S
(((R)-12-((S)-7,8-Difluoro-6,11-Dihydrodibenzo[b,e]Thiepin-11-yl)-6,8-Dioxo-3,4,6,8,12,12a-Hexahydro-1H-[1,4]Oxazino[3,4-c]Pyrido[2,1-f][1,2,4]Triazin-7-yl)oxy)Methyl Methyl Carbonate; ({(12aR)-12-[(11S)-7,8-Difluoro-6,11-Dihydrodibenzo[b,e]Thiepin-11-yl]-6,8-Dioxo-3,4,6,8,12,12a-Hexahydro-1H-[1,4]Oxazino[3,4-c]Pyrido[2,1-f][1,2,4]Triazin-7-yl}oxy)Methyl Methyl Carbonate
Brief Introduction
Baloxavir axetil is an innovative cap dependent endonuclease inhibitor. It is also one of the few new drugs in the world that can inhibit the proliferation of influenza virus.
CAS:633-65-8
Molecular Formula:C20H18ClNO4
Berberine Chloride; Berberinium Chloride; Berberine Hydrochloride; Berberine (Chloride); Unii-Uot4O1Byv8; Berberin Hydrochloride; 9,10-Dimethoxy-5,6-Dihydro-[1,3]Dioxolo[4,5-G]Isoquinolino[3,2-A]Isoquinolin-7-Ium Chloride; Benzodioxide
Brief Introduction
Berberine hydrochloride has been used in clinic for a long time as antipyretic and antibacterials. Berberine hydrochloride has inhibitory effect on Shigella dysentery, Escherichia coli, Diplococcus pneumoniae, Staphylococcus aureus, Streptococcus, typhoid bacillus and Amoeba protozoa. It is commonly used in the treatment of bacillary dysentery, acute gastroenteritis, chronic cholecystitis, conjunctivitis, suppurative otitis media and other diseases, and has significant curative effect. Berberine hydrochloride is an isoquinoline alkaloid, which exists in many plants such as Berberidaceae.
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