2-(4-Methylpiperazin-1-yl)-N-[(E)-(5-Nitrofuran-2-yl)Methylideneamino]Acetamide; Nifurpiponum [INN-Latin]; 5-Nitro-Furfural-<(4-Methyl-Piperazino)-Acetylhydrazon>; (4-Methyl-Piperazin-1-yl)-Acetic acid (5-Nitro-Furan-2-Ylmethylene)-Hydrazide; 5-Nitro-2-Furaldehyde 4-Methylpiperazinoacethydrazone; 5-Nitro-2-Furaldehyde N'-Methylpiperazinoacethydrazone

Brief Introduction

Anti infectives

Boceprevir

CAS:394730-60-0

Molecular Formula:C27H45N5O5

Alias

More Information

Boceprevir Metabolites; Victrelis; [14C]-Boceprevir; Bocepravir; (1R,2S,5S)-N-(4-Amino-1-Cyclobutyl-3,4-Dioxobutan-2-yl)-3-((S)-2-(3-(tert-Butyl)Ureido)-3,3-Dimethylbutanoyl)-6,6-Dimethyl-3-Azabicyclo[3.1.0]Hexane-2-Carboxamide; 3-{[(1R,2S,5S)-3-[(2S)-2-[(tert-Butylcarbamoyl)Amino]-3,3-Dimethylbutanoyl]-6,6-Dimethyl-3-Azabicyclo[3.1.0]Hexan-2-yl]Formamido}-4-Cyclobutyl-2-Oxobutanamide

Brief Introduction

Boprivir is an oral inhibitor of hepatitis C virus nonstructural protein 3 / 4A serine protease. They act directly on the functional region of viral enzyme, namely viral protease.

Avibactam

CAS:1192500-31-4

Molecular Formula:C7H11N3O6S

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(E)-7-Fluoro-3-Methylhept-4-en-2-one; (2S,5R)-7-Oxo-6-(Sulfooxy)-1,6-Diazabicyclo[3.2.1]Octane-2-Carbox Amide; 4-Hepten-2-one,7-Fluoro-3-Methyl-,(E); Trans-7-Fluoro-3-Methyl-4-Hepten-2-one; Trans-7-oxo-6-(Sulphooxy)-1,6-Diazabicyclo[3.2.1]Octane-2-Carboxamide; Avibactam free acid; NXL104; AVE-1330A free acid

Brief Introduction

Avibactam is a member of the class of azabicycloalkanes that is (2S,5R)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide in which the amino hydrogen at position 6 is replaced by a sulfooxy group. Used (in the form of its sodium salt) in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. It has a role as an antibacterial drug, an antimicrobial agent and an EC 3.5.2.6 (beta-lactamase) inhibitor. It is a monocarboxylic acid amide, a member of ureas, an azabicycloalkane and a hydroxylamine O-sulfonic acid. It is a conjugate acid of an avibactam(1-).

Penciclovir Triphosphate

CAS:120082-86-2

Molecular Formula:C10H18N5O12P3

Brief Introduction

Phosphorylation to penciclovir triphosphate Triphosphates can inhibit viral DNA polymerase, thereby affecting the replication of the virus in cells

Nirmatrelvir

CAS:2628280-40-8

Molecular Formula:C23H32F3N5O4

Alias

More Information

Paxlovid; (1R,2S,5S)-N-[(1S)-1-Cyano-2-[(3S)-2-Oxopyrrolidin-3-yl]Ethyl]-3-[(2S)-3,3-Dimethyl-2-[(2,2,2-Trifluoroacetyl)Amino]Butanoyl]-6,6-Dimethyl-3-Azabicyclo[3.1.0]Hexane-2-Carboxamide; (1R,2S,5S)-N-((1S)-1-Cyano-2-((3S)-2-Oxopyrrolidin-3-yl)Ethyl)-6,6-Dimethyl-3-(3-Methyl-N-(Trifluoroacetyl)-L-Valyl)-3-Azabicyclo(3.1.0)Hexane-2-Carboxamide; (1R,2S,5S)-N-[(1S)-1-Cyano-2-[(3S)-2-Oxopyrrolidin-3-yl]Ethyl]-3-[(2S)-3,3-Dimethyl-2-(2,2,2-Trifluoroacetamido)Butanoyl]-6,6-Dimethyl-3-Azabicyclo[3.1.0]Hexane-2-Carboxamide; (1R,2S,5S)-N-((S)-1-Cyano-2-((S)-2-Oxopyrrolidin-3-yl)Ethyl)-3-((S)-3,3-Dimethyl-2-(2,2,2-Trifluoroacetamido)Butanoyl)-6,6-Dimethyl-3-Azabicyclo[3.1.0]Hexane-2-Carboxamide; 3-Azabicyclo(3.1.0)Hexane-2-Carboxamide, N-((1S)-1-Cyano-2-((3S)-2-oxo-3-Pyrrolidinyl)Ethyl)-3-((2S)-3,3-Dimethyl-1-oxo-2-((2,2,2-Trifluoroacetyl)Amino)Butyl)-6,6-Dimethyl-, (1R,2S,5S)-; 3-Azabicyclo[3.1.0]Hexane-2-Carboxamide, N-[(1S)-1-Cyano-2-[(3S)-2-oxo-3-Pyrrolidinyl]Ethyl]-3-[(2S)-3,3-Dimethyl-1-oxo-2-[(2,2,2-Trifluoroacetyl)Amino]Butyl]-6,6-Dimethyl-, (1R,2S,5S)-; (1S,3aS,4aR)-N-[(1S)-1-Cyano-2-[(3S)-2-Oxotetrahydro-1H-Pyrrol-3-yl]Ethyl]-2-[(2S)-3,3-Dimethyl-1-oxo-2-[(Trifluoroacetyl)Amino]Butyl]-4,4-Dimethyl-2,3,3a,4a-Tetrahydro-1H-Cyclopropa[1,2-c]Pyrrole-1-Carboxamide

Brief Introduction

Nirmatrelvir is an effective oral inhibitor of SARS coronavirus 3C like protease.

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