4-Amino-1-[(2R,3R,4R,5R)-3-Fluoro-4-Hydroxy-5-(Hydroxymethyl)-3-Methyloxolan-2-Yl]Pyrimidin-2-One; 2'-Deoxy-2'-Fluoro-2'-C-Methylcytidine; 2'-Fluoro-2'-C-Methylcytidine; R-7128; Psi6130; R-1656; Cytidine, 2'-Deoxy-2'-Fluoro-2'-Methyl-, (2'R)-

Brief Introduction

PSI-6130 is an experimental treatment for hepatitis C. PSI-6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors that was created by chemist Jeremy L. Clark. Specifically, PSI-6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B.

4-Chloro-3-Methylbenzoic Acid

CAS:7697-29-2

Molecular Formula:C8H7ClO2

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4-Chloro-3-Methylbenzoesaeure; 3-Methyl-4-Chlorobenzoic Acid; 4-Chlor-M-Toluylsaeure; Benzoic Acid, 4-Chloro-3-Methyl-; 4-Chlor-3-Methyl-Benzoesaeure; 4-Chloro-3-Methyl-Benzoic Acid; 4-Chloro-M-Toluic Acid

Brief Introduction

4-Chloro-3-methylbenzoic Acid is used as a reactant in the preparation of tipifarnib analogs as cancer drugs agains chagas disease.

Thiamine Ion

CAS:70-16-6

Molecular Formula:C12H17N4OS+

Alias

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Thiamine; Thiamine Cation; Vitamin B1; Aneurin

Brief Introduction

Thiamine is a heat-labile and water-soluble essential vitamin, belonging to the vitamin B family, with antioxidant, erythropoietic, mood modulating, and glucose-regulating activities. Thiamine reacts with adenosine triphosphate (ATP) to form an active coenzyme, thiamine pyrophosphate. Thiamine pyrophosphate is necessary for the actions of pyruvate dehydrogenase and alpha-ketoglutarate in carbohydrate metabolism and for the actions of transketolase, an enzyme that plays an important role in the pentose phosphate pathway. Thiamine plays a key role in intracellular glucose metabolism and may inhibit the action of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine may also protect against lead toxicity by inhibiting lead-induced lipid peroxidation.

6-Bromoquinoline-3-Carbaldehyde

CAS:6155-68-6

Molecular Formula:C6H10O6Zn

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L-Zinc; Zinc &Zinc Dl-Lactate; Dl-Milchsaeure,Zinklactat; L-Zinc Lactatel; Zincum Lactate; L-Zinc Lactate; Ferrous &L-Lactate Sodium &Potassium &Dl-Lactic Acid,Zinc Lactate; Ammonium Salts; Zinc Salt Of Lactic Acid; Zn Lactate

Brief Introduction

乳酸锌用于补锌食品、营养口服液、儿童补锌片剂及冲剂的生产。

Canagliflozin Hemihydrate

CAS:928672-86-0

Molecular Formula:C48H52F2O11S2

Alias

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(2S,3R,4R,5S,6R)-2-[3-[[5-(4-Fluorophenyl)Thiophen-2-Yl]Methyl]-4-Methylphenyl]-6-(Hydroxymethyl)Oxane-3,4,5-Triol,Hydrate; Unii-0Sac974Z85; Canagliflozin Hydrate; Ta-7284; Invokan; Canagliflozin Hemihydrate Inn; Unii-0Sac974Z85

Brief Introduction

Kangliflozin hemihydrate is a kind of hydrate of kangliflozin. The chemical name of canagliflozin is 1-（ β- D-glucopyranosyl) - 4-methyl-3 - [5 - (4-fluorophenyl) - 2-thienylmethyl] benzene was developed by Johnson & Johnson's subsidiary, Janssen Pharmaceutical Company. Canglitazin is a chemical Book selective sodium glucose transporter type 2 (sglt-2) inhibitor, which can specifically inhibit the reabsorption of glucose by the kidney, so that excess glucose can be excreted from the urine, thus directly reducing the blood glucose level. The drug was approved by FDA in March 29, 2013 for the treatment of type II diabetes, the trade name is Invokana.

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