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Pharmaceutical Intermediates

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CAS:875781-43-4
Molecular Formula:C6H4BrN3
2-Bromo-5H-Pyrrolo[2,3-b]Pyrazine; 4H-Pyrrolo[2,3-b]Pyrazine, 2-Bromo-
Brief Introduction
5-bromo-4,7-diazabindole is used as an intermediate in organic synthesis and medicine.
CAS:923288-90-8
Molecular Formula:C28H25ClF3N7O2
Nilotinib Monohydrochloride Monohydrate; Nilotinib HCl Monohydrate; Nilotinib HCl Hydrate; Nilotinib (Monohydrochloride Monohydrate); Nilotinib Hydrochloride Hydrate; 4-Methyl-N-[3-(4-Methylimidazol-1-yl)-5-(Trifluoromethyl)Phenyl]-3-[(4-Pyridin-3-Ylpyrimidin-2; 4-Methyl-N-(3-(4-Methyl-1H-Imidazol-1-yl)-5-(Trifluoromethyl)Phenyl)-3-((4-(Pyridin-3-yl)Pyrimidin-2-yl)Amino)Benzamide Hydrochloride Hydrate
Brief Introduction
Nilotinib intermediate
CAS:1428243-26-8
Molecular Formula:C16H20BrNO3
(3R,4S)-3-(2-Bromoacetyl)-4-Ethyl-1-Pyrrolidinecarboxylic acid Phenylmethyl Ester; (3R,4S)-Benzyl 3-(2-Bromoacetyl)-4-Ethylpyrrolidine-1-Carboxylate
Brief Introduction
Benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate is a key intermediate of upatinib. At the beginning of 2018, the oral Jak1 selective inhibitor upadacitinib (abt-494), developed by abbvie in the United States once every day for the treatment of adult moderate and severe atopic dermatitis, was recognized as a breakthrough therapy by FDA.
CAS:1415831-82-1
Molecular Formula:C11H10INO2
Brief Introduction
As an organic synthesis intermediate and pharmaceutical intermediate, it is mainly used in laboratory R & D process and chemical and pharmaceutical production process.
CAS:915095-99-7
Molecular Formula:C31H35ClO11
(1S)-1,5-Anhydro-2,3,4,6-Tetra-O-Acteyl-1-C-[4-Chloro-3-[[4-[[(3S)-Tetrahydrofu-ran-3-yl]oxy]Phenyl] Methyl]Phenyl]-D-Glucitol; D-Glucitol, 1,5-Anhydro-1-C-[4-Chloro-3-[[4-[[(3S)-Tetrahydro-3-Furanyl]oxy]Phenyl]Methyl]Phenyl]-, 2,3,4,6-Tetraacetate, (1S)-; D-Glucitol, 1,5-Anhydro-1-C-[4-Chloro-3-[[4-[[(3S)-Tetrahydro-3-Furanyl]oxy]Phenyl]Methyl]Phenyl]-, Tetraacetate, (1S)- (9CI)
Brief Introduction
Acetyl englitazin is an intermediate for the synthesis of englitazin.Empagliflozin, CO developed by Blyngju G John and Eli Lilly, is a sodium glucose co transporter (SGLT2) inhibitor that can be used in the treatment of type 2 diabetes. At present, it has been listed and sold in the United States, Europe, Japan and other countries.
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