Pharmaceutical Intermediates

Pentaerythritol, as a quaternary alcohol, is easy to be esterified to form acids and esters, so it is mostly used as raw material of alkyd resin coatings, mainly used as building coatings and automotive primer. Pentaerythritol tetranitrate can be obtained by esterification of pentaerythritol and concentrated nitric acid at 5 ~ 15 ℃ in industry. It is a kind of high-performance and strong explosive with higher explosive power than TNT. It is often used as booster or mixed with TNT. It was used extensively in the Second World War. It is a long-acting vasodilator and can treat angina pectoris. Pentaerythritol rosin ester can be prepared by the reaction of pentaerythritol and rosin acid. It can be mixed with dry oil to obtain a coating with good hardness, water resistance and weather resistance. It can be used for varnishes, floor inks, etc. An alkyd resin coating can be prepared by esterification polycondensation of pentaerythritol or glycerin with phthalic anhydride and fatty acid. The properties of alkyd resin can be improved by using different kinds and different amounts of fatty acids, making it suitable for various needs of coatings. It is widely used as metal, wood surface coating, for bridges, railways, derricks, housing construction and other commonly used industrial paint and architectural paint. Alkyd resin has developed rapidly since it entered industrial production in 1927 due to its low price, easy availability of raw materials, easy modification, strong adaptability and good comprehensiveness.

Produced as an inhibitor, an antioxidant, and an intermediate in the synthesis of dyes, motor fuels, and oils; in photographic processing; and naturally in certain plant species, Hydroquinone is a phenol derivative with antioxidant properties that can cause toxicity in several organs, notably the kidney. Used as a topical treatment for skin hyperpigmentation and in various cosmetic products, it is metabolized mainly to glutathione conjugates and forms mutagenic DNA adducts in in-vitro systems.

Crosslinked polyvinylpyrrolidone (PVPP) is a kind of crosslinked polymer insoluble in water, strong acid, strong base and general organic solvents, which is polymerized by vinyl pyrrolidone monomer under specific conditions. As an important polymer fine chemical product, PVPP has many excellent and unique properties and has been widely used in cosmetics, food, medicine and other fields.

4-hydroxythiobenzamide is an intermediate of organic synthesis and pharmaceutical research and development. In the process of organic synthesis and pharmaceutical research and development, it can be used to synthesize febuxostat.

This product is mainly used to synthesize pigment yellow and pigment orange.