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CAS:875781-43-4
Molecular Formula:C6H4BrN3
2-Bromo-5H-Pyrrolo[2,3-b]Pyrazine; 4H-Pyrrolo[2,3-b]Pyrazine, 2-Bromo-
Brief Introduction
5-bromo-4,7-diazabindole is used as an intermediate in organic synthesis and medicine.
CAS:923288-90-8
Molecular Formula:C28H25ClF3N7O2
Nilotinib Monohydrochloride Monohydrate; Nilotinib HCl Monohydrate; Nilotinib HCl Hydrate; Nilotinib (Monohydrochloride Monohydrate); Nilotinib Hydrochloride Hydrate; 4-Methyl-N-[3-(4-Methylimidazol-1-yl)-5-(Trifluoromethyl)Phenyl]-3-[(4-Pyridin-3-Ylpyrimidin-2; 4-Methyl-N-(3-(4-Methyl-1H-Imidazol-1-yl)-5-(Trifluoromethyl)Phenyl)-3-((4-(Pyridin-3-yl)Pyrimidin-2-yl)Amino)Benzamide Hydrochloride Hydrate
Brief Introduction
Nilotinib intermediate
CAS:1428243-26-8
Molecular Formula:C16H20BrNO3
(3R,4S)-3-(2-Bromoacetyl)-4-Ethyl-1-Pyrrolidinecarboxylic acid Phenylmethyl Ester; (3R,4S)-Benzyl 3-(2-Bromoacetyl)-4-Ethylpyrrolidine-1-Carboxylate
Brief Introduction
Benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate is a key intermediate of upatinib. At the beginning of 2018, the oral Jak1 selective inhibitor upadacitinib (abt-494), developed by abbvie in the United States once every day for the treatment of adult moderate and severe atopic dermatitis, was recognized as a breakthrough therapy by FDA.
(2R,3R)-3-(2,5-Difluorophenyl)-3-Hydroxy-2-Methyl-4-(1H-1,2,4-Triazol-1-yl)Thiobutyramide; (2R,3R)-3-(2,5-Difluorophenyl)-3-Hydroxy-2-Methyl-4-(1,2,4-Triazol-1-yl)Butanethioamide; (2R,3R)-3-(2,5-Difluoro-Phenyl)-3-Hydroxy-2-Methyl-4-[1,2,4]Triazol-1-Ylthiobutyramide; (2R,3R)-3-(2,5-Difluoro-Phenyl)-3-Hydroxy-2-Methyl-4-[1,2,4]Triazol-1-Ylthiobutyrarnide; rel-(|AR,|AR)-|A-(2,5-Difluorophenyl)-|A-Hydroxy-|A-Methyl-1H-1,2,4-Triazole-1-Butanethioamide
Brief Introduction
Isaconazole intermediate is an intermediate for the synthesis of isaconazole (i777830), an antifungal agent based on triazole, which is used to treat invasive fungal infection.
CAS:1315478-13-7
Molecular Formula:C13H21N3O2
Fimasartan Intermediate; 2-Butyl-1,6-Dihydro-N,N,4-Trimethyl-6-oxo-5-Pyrimidineacetamide; Butyl-1,6-Dihydro-N,N,4-Trimethyl-6-oxo-5-Pyrimidineacetamide
Brief Introduction
2-(2-Butyl-4-Hydroxy-6-Methylpyrimidin-5-yl)-N,N-Dimethylacetamide can be used as Fimasartan Intermediate.
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