Digestive System Drugs

It is used as textile mordant, agricultural pesticide, water bactericide and feed additive, and for copper plating.

It can be used to manufacture ceramics, enamel, refractory crucible and refractory brick, and can also be used as polishing agent, adhesive, filler of paint and paper, accelerator and activator of neoprene and fluororubber. After mixing with magnesium chloride and other solutions, magnesium oxide cement can be prepared. In medicine, it is used as antacid and laxative, for excessive gastric acid, gastric and duodenal ulcer, and also for glass, dye, phenolic plastics and other industries. Food grade is used as decolorizing agent for refining granulated sugar, pH regulator for ice cream powder, etc.

Sodium sulfate is an important chemical raw material. It is the main raw material for the production of sodium sulfide, sodium silicate and other chemical products. It can also be used as a filler for synthetic detergent and a cooking agent for the manufacture of sulfate pulp in the paper industry. Sodium sulfate is also called sodium sulfate, anhydrous mirabilite and anhydrous tannite. White monoclinic fine crystal or powder. The relative density is 2.68 and the melting point is 884 ℃. Soluble in water, the aqueous solution is neutral. Soluble in glycerine oil, insoluble in ethanol, exposed to air, easy to absorb water and become aqueous sodium sulfate. It is a homogeneous polycrystalline substance, which is rhombic at 32.4 ~ 223 ℃, monoclinic crystal at higher temperature, and hexagonal crystal at 241 ℃. When crystallized from solution, it has affinity for iron, iron compounds and various organic substances; Anhydrous sodium sulfate with high purity and fine particles is called sodium sulfate.

Rifaximin, a rifamycin derivative, was developed by Alpha Company of Italy. It was listed in Italy as an anti infective diarrhea drug in 1987, and has been widely used abroad since then. It was approved by SFDA in 2004 and has been clinically used in China. Rifamycin is a semi synthetic antibiotic with broad antibacterial spectrum and strong antibacterial effect. It can form a high blood concentration in the intestinal tract. It can inhibit Staphylococcus aureus and Streptococcus faecalis in Gram-positive aerobic bacteria, Salmonella, Shigella, Escherichia coli and Yersinia enterocolitica in Gram-negative aerobic bacteria, Bacteroides in gram positive anaerobes have high antibacterial activity. Its mechanism of action is to inhibit the bacterial polymerase, block the transcription of RNA, and then inhibit the synthesis of bacterial protein, thus reducing the production of ammonia. Its antibacterial effect is characterized by: 1) strong antibacterial force, broad antibacterial spectrum, bactericidal effect on most Gram-positive bacteria and Gram-negative bacteria (including aerobic and anaerobic bacteria), and stronger effect on Gram-positive bacteria than Gram-negative bacteria; 2) It is not absorbed by the gastrointestinal tract and has high concentration in the intestinal tract. It can rapidly play an antibacterial role in the local area by killing intestinal pathogens, and does not need to be combined with the use of intestinal antispasmodics and adsorbents.

Gastrin is a large glycoprotein that protects the gastrointestinal tract from acids, proteases, pathogenic microorganisms and mechanical trauma.