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Circulatory System Drugs

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CAS:16051-77-7
Molecular Formula:C6H9NO6
1,4:3,6-Dianhydro-D-Glucitol 5-Nitrate; Isosorbide 5-Mononitrate; Isosorbide Nitrate; Corangin
Brief Introduction
Isosorbide mononitrate is the common name of 1,4:3,6-didehydrated-d-sorbitol-5 mononitrate, also known as isosorbide 5-nitrate. It is the main bioactive metabolite of isosorbide dinitrate. The main pharmacological action is to relax vascular smooth muscle. The clinical dosage forms of include: ordinary tablets, sustained-release preparations and injections, which are mainly used for the long-term treatment of guanye disease; Prevention of angina pectoris; Treatment of persistent angina pectoris after myocardial infarction; Combined with digitalis or diuretics to treat chronic congestive heart failure; To treat simple systolic hypertension, hypertensive crisis and perioperative acute hypertension in the elderly.
CAS:163222-33-1
Molecular Formula:C24H21F2NO3
(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-Fluorophenyl)-3-Hydroxypropyl]-4-(4-Hydroxyphenyl)Azetidin-2-One; Ezetrol; Zetia; Ezetimib; [Ezetimide]; Ezetimibe-001; Ticagrelor And Its Intermediate; 1-(4-Fluorophenyl)-3-[3-(4-Fluorophenyl)-3-Hydroxy-Propyl]-4-(4-Hydroxyphenyl)-Azetidin-2-One; Ezatimibe; Zetia/Vytorin; Sch 60969; Ezetimibe, >=99%; Ezitimibe
Brief Introduction
Ezetimibe is a white crystalline powder, very soluble in ethanol, methanol and acetone, insoluble in water, with a melting point of about 163 ℃ and stable at room temperature. Ezetimibe only acts on the small intestine and reduces the transport of intestinal cholesterol to the liver and its storage by inhibiting the absorption of cholesterol; It can enhance the clearance of cholesterol in the blood and reduce the level of plasma cholesterol.
CAS:20123-80-2
Molecular Formula:C12H10CaO10S2
Calcium Dobesilate Mnohydrate; Calcium Bis(2,5-Dihydroxybenzenesulfonate); Calcium,2,5-Dihydroxybenzenesulfonate; 2,5-Dihydroxybenzenesulfonic Acid Calcium Salt; 2,5-Dihydroxybenzenesulfonic Acid Calcium
Brief Introduction
This product is a vasodilator that selectively acts on the capillary wall. It not only can adjust and improve the permeability and brittleness of capillary wall, but also inhibit bradykinin and other active substances. It is mainly used for treating various causes of capillary diseases, such as diabetic retinopathy, varicose veins, phlebitis, leg spasms, phlegm itching dermatitis and so on. This product has high bioavailability, low toxicity and high therapeutic index. It is an ideal drug for the treatment of capillary diseases.
Fimasartan; Br-A-657K; 2-(1-((2'-(2H-Tetrazol-5-Yl)-[1,1'-Biphenyl]-4-Yl)Methyl)-2-Butyl-4-Methyl-6-Oxo-1,6-Dihydropyrimidin-5-Yl)-N,N-Dimethylethanethioamide; Fimasartan [Inn]; Unii-P58222188P
Brief Introduction
Famasartan is a new selective AT1 receptor antagonist developed by Baoning pharmaceutical in Korea. It shows rapid and effective antihypertensive effect in many types of hypertension. In September 2010, the South Korean FDA approved the listing, with sales of more than 100 million in 13 years. In 2013, it was listed in Russia, Mexico and Brazil. Preclinical studies show that it is well tolerated. Compared with losartan, it has faster antihypertensive effect and better antihypertensive effect.
CAS:274901-16-5
Molecular Formula:C17H25N3O2
Galvus; Laf 237; Unii-I6B4B2U96P; Xiliarx; Jalra; (2S)-1-[2-[(3-Hydroxy-1-Adamantyl)Amino]Acetyl]Pyrrolidine-2-Carbonitrile
Brief Introduction
Vee Glenn Dean is another oral administration of two peptidyl peptidase -IV (DPP-IV) inhibitor, after the administration of Western drug. It was approved by the Swiss Nuo Hua (Novartis) Pharmaceutical Company Limited in 2008 to be listed in the European Union for the treatment of type 2- diabetes.
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