Dasatinib Tablets; Sprycel; Bms-354825; Bms 354825; N-(2-Chloro-6-Methylphenyl)-2-[[6-[4-(2-Hydroxyethyl)Piperazin-1-Yl]-2-Methylpyrimidin-4-Yl]Amino]-1,3-Thiazole-5-Carboxamide

Brief Introduction

Dasatinib is a gray white to yellow solid chemical. Chemical name: n - (2-chloro-6-methylphenyl) - 2 - [[6 - [4 - (2-hydroxyethyl) - 1-piperazinyl] - 2-methyl-4-pyrimidinyl] amino] - 5-thiazolamide. Dasatinib is an antitumor drug. Clinically, it mainly treats adult patients with Philadelphia chromosome positive (Ph +) chronic myeloid leukemia (CML) in chronic phase, accelerated phase and acute phase (acute granulosis and acute lymphoblasty).

3,5-Dimethylpiperidine

MSDS

CAS:35794-11-7

Molecular Formula:C7H15N

Alias

More Information

3,5-Me2Piperidine; 3,5-Lupetidine; 3,5-Dimethylpiperidin; Piperidine, 3,5-Dimethyl-; Piperidine,3,5-Dimethyl; 3,5-Cis-Dimethylpiperidine; 3.5-Dimethylpiperidine; Hexahydro-3,5-Lutidine

Brief Introduction

3,5-Dimethylpiperidines are chemical compounds with the formula C5H8(CH3)2NH. Two diastereomers exist: the achiral R,S isomer and the chiral R,R/S,S enantiomeric pair.

Lapatinib Ditosylate Hydrate

MSDS

CAS:388082-78-8

Molecular Formula:C43H44ClFN4O11S3

Alias

More Information

Lapatinib Ditosylate Monohydrate; Lapatinib Ditosilate Monohydrate; N-(3-Chloro-4-((3-Fluorophenyl)Methoxy)Phenyl)-6-(5-(((2-(Methylsulfonyl)Ethyl)Amino)Methyl)-2-Furanyl)-4-Quinazolinamine Bis(4-Methylbenzenesulfonate) Monohydrate; N-(3-Chloro-4-{[(3-Fluorophenyl)Methyl]Oxy}Phenyl)-6-[5-({[(2-Methylsulfonyl)Ethyl]Arnino}Methyl)-2-Furanyl]-4-Quinazolinamine Bis(4-Methylbenzenesulfonate) Monohydrate; Lapatinib Ditosylate; Benzenesulfonic Acid

Brief Introduction

It is used in combination with capecitabine for the treatment of advanced or metastatic breast cancer with overexpression and previous treatment including anthracycline, paclitaxel and trastuzumab (Herceptin).

Lenvatinib

MSDS

CAS:417716-92-8

Molecular Formula:C21H19ClN4O4

Alias

More Information

E7080,E 7080; Lenvatinib (E7080); 4-[3-Chloro-4-(Cyclopropylcarbamoylamino)Phenoxy]-7-Methoxyquinoline-6-Carboxamide; Lenvima

Brief Introduction

Lovatinib, trade name: lenvima, is an oral multi-target tyrosine kinase (RTK) inhibitor. In addition to inhibiting RTK related to angiogenesis and carcinogenic signal pathway, lovatinib can also selectively inhibit the kinase activity of vascular endothelial growth factor (VEGF) receptors, including vegf1, vegf2, vegf3, FGFR and PDGFR α、 Kit and ret. The drug was approved by FDA on February 13, 2015 for the treatment of locally recurrent or metastatic, radioactive iodine refractory and progressive differentiated thyroid cancer (DTC).

Emodin

MSDS

CAS:518-82-1

Molecular Formula:C15H10O5

Alias

More Information

Ecdyson; 6-Methyl-1,3,8-Trihydroxyanthraquinone; Emodin 99; 1,3,8-Trihydroxy-6-Methylanthraquinone; 9,10-Anthracenedione, 1,3,8-Trihydroxy-6-Methyl-; Emodine; 1,3,8-Trihydroxy-6-Methylanthracene-9,10-Dione; Schuttgelb; Alatinone; 1,3,8-Tri-Hydroxy-6-Methyl-Anthra-Quinone; Emdin; Archin; Emodol; 1,3,8-Trihydroxy-6-Methyl-9-10-Anthracenedione

Brief Introduction

Emodin is a natural compound extracted from Chinese herbal medicines such as rhubarb and Polygonum cuspidatum. It has many pharmacological effects, such as anti-inflammatory, anti-virus, anti-tumor and so on. Emodin is mainly used for antifeedant, anti-inflammatory, anti mutation, anti-corrosion, anti-cancer (chest), anti ulcer, anti-virus, catharsis, gonadotropic, anti epidemic, insecticide, defecation, antispasmodic and hemostatic agents.

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