API & Intermediate

Ursodeoxycholic acid is a chemical preparation of natural bile acid isolated from bear bile juice. It is a stereoisomer of chenodeoxycholic acid. Its litholytic effect and curative effect are similar to chenodeoxycholic acid, but the course of treatment is short and the dosage is small. It is a kind of hydrophilic cholic acid and a kind of cholesterol stone dissolving agent. It can reduce the secretion of cholesterol by liver, reduce the saturation of cholesterol in bile, promote the secretion of bile acid, increase the solubility of cholesterol in bile, dissolve cholesterol stones or prevent the formation of stones. It can increase the amount of bile secretion, relax the sphincter of bile duct mouth, produce cholagogic effect, which is conducive to the discharge of stones. This product can not dissolve other types of gallstones. Ursodeoxycholic acid is suitable for the treatment of cholesterol gallstones, hyperlipidemia, bile secretion disorders, primary biliary cirrhosis, chronic hepatitis, bile reflux gastritis and prevention of acute rejection and reaction of liver transplantation. The stone dissolving effect of this product is slightly weaker than that of chenodeoxycholic acid.

Milbeoxime is a macrolide antibody endoparasite and an oxime derivative of milbemycin A3 and A4. Milbeoxime can bind glutamate gated chloride channels and act on intestinal nematodes, lung and heart worms. Milbeoxime has a broad spectrum of antiparasitic effects, and has good repellent and killing effects on internal and external parasites, especially nematodes and arthropods.

Riboflavin sodium phosphate is a prodrug of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). It is also known as vitamin B2 sodium phosphate, flavin mononucleotide sodium and riboflavin-5 '- (dihydrophosphate) monosodium salt in Chinese. FMN and fad are important cofactors of flavinase family. Flavinases catalyze many biochemical reactions, the most typical of which is redox reaction. They are the key factors of cell respiration.

For the treatment of glaucoma.

Tetraacetylribose is an important intermediate for the production of antiviral Triazole Nucleoside in the pharmaceutical industry. It is mainly used to synthesize broad-spectrum antiviral drug ribavirin. It is also the starting material for the synthesis of nucleoside compounds.