MANNITOL
FUNCTIONAL CHARACTERISTICS
Mannitol(D-Mannitol) is a type of functional sugar alcohl with excellent performance.Its molecular formula is C6H14O6 and molecular weight is 182.17 .It is nonhygroscopic,odorless,white or colorless crystal powder.It can be wedely used in pharmaceutical,food,and other industries.
Sweet taste-sweet degree | 55%-65% of sucrose's. |
Low calory | 1.6kc/g,taking 40% of sucrose's. |
Nonhyfroscopic | the only which nonhygroscopic in hexahydric sugar alchol. |
Steady nature | No reaction with other pharmaceutical material. |
Delay calcium phosphate | Prevent the-Added in gum to accelerate the absorption for calcium sediment of calcium. |
Main application
Medicine: Antihypertensive agents, diuretics, dehydration, laxative, pharmaceutical tablet excipients and filler, preparation with mannitol, mannitol hexanicotinate
Food: sweeteners or anti adherent of sugarless gum, making ice cream, making the flavored sugar of the candy chocolate, and to be used in beverage, candy, and other food.
Others: to replace glycerol in the production of toothpaste, Mannitol polyurethane, mannitol anhydride oleic acid ester, electrolytic capacitor of the electrolyte, and some good medium of micro-organisims.
STANDARD
FOOD ADDITIVE:D-MANNITOL :NO.8 . 2011 announcement of health Ministry
API MANNITOL : CP2015、BP2015、USP38
Mannitol is a six carbon polyol extracted from brown algae cells. It has two configurations: D and L. L configuration is a synthetic product, which does not exist in nature. D configuration is widely distributed in the plant kingdom. In particular, the content of mannitol in marine brown algae of kelp family is very high. Mannitol is a storage material in brown algae cells. Kelp and other large brown algae are the main raw materials for the extraction of mannitol. Mannitol extracted from kelp and nicotinic acid mannitol ester synthesized from nicotinic acid can significantly alleviate angina pectoris and have a good curative effect on hyperlipidemia. It can treat diseases such as high cholesterol, hypertension and arteriosclerosis. Mannitol is also a dehydrating agent, which can be used in medical treatment. When its 20% solution is injected into the vein, it is rarely decomposed in the body, resulting in a temporary increase in blood osmotic pressure, so as to make the water in the tissue enter the blood, so as to reduce the edema of the tissue. When mannitol is filtered from the glomerulus, it is not easy to be reabsorbed in the renal tubules, which increases the osmotic pressure of the original urine in the renal tubules and brings out a large amount of water to play a diuretic role.
IUPAC
(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
SMILES
C(C(C(C(C(CO)O)O)O)O)O
Shandong, China
