β-Nicotinamide Mononucleotide

CAS No.: 1094-61-7

Molecular formula: C₁₁H₁₅N₂O₈P

Application:

APIs, intermediates, health products, cosmetics

Product introduction:

Nicotinamide mononucleotide plays an important role in human cell energy production. It participates in the synthesis of intracellular NAC (nicotinamide adenine dinucleotide, an important coenzyme of cell energy conversion). Nicotinamide is a derivative of vitamin B3. NAD + is a molecule with multiple functions in vivo, which is mainly realized by promoting cell signal transduction enzymes called sirtuins. These enzymes are essential for normal function, among which s1rt1 (with seven silent regulatory proteins) is particularly unique. Studies have shown that it has high activity after caloric restriction, and caloric restriction itself brings many benefits, including signs of life extension. There is no doubt that further tests show that the increase of s1rt1 level can prevent metabolic decline and disease.

Is it safe to take NMN for a long time?

NMN itself is a natural substance in the human body and also exists in many foods. It is pure natural and harmless. Studies have confirmed that NMN supplementation will not affect the activities of various enzymes in the supplementary synthesis pathway, and oral Nampt, PARP, Nmnat and other activities have no effect, which directly changes the level of NAD + in vivo.

The research shows that the elderly over 65 years old with about 70kg should supplement about 600mg NMN every day, and the young people aged about 45 should supplement about 300mg. This is equivalent to eating about 32g of soybeans or broccoli every day, or under the condition of ensuring complete absorption. Of course, this can not be achieved at all. Therefore, it is particularly important to supplement NMN from non food sources.