Brincidofovir 是一种烷氧基烷基酯前药，含有合成的无环核苷单磷酸类似物西多福韦，通过其膦酸酯基团与脂质3-十六烷氧基-1-丙醇相连，对双链 DNA 病毒具有抗病毒活性。口服给药后，brincidofovir 穿过肠壁并穿透目标病毒感染细胞，然后被裂解为游离的抗病毒药物西多福韦。反过来，西多福韦被丙酮酸激酶磷酸化为其活性代谢物西多福韦二磷酸。西多福韦二磷酸与核苷酸结构相似，与脱氧胞嘧啶 5-三磷酸 ( dCTP )竞争病毒 DNA 聚合酶，并整合到不断增长的病毒 DNA 链中。因此，它可以防止 DNA 进一步聚合并破坏病毒的 DNA 复制。与静脉内给予的西多福韦相比，十六烷氧基丙基-西多福韦显示出更好的口服生物利用度、更低的毒性和增强的细胞渗透。

2-Fluorobenzyl Bromide

MSDS

CAS:446-48-0

Molecular Formula:C7H6BrF

Alias

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1-(Bromomethyl)-2-Fluorobenzene; 2-Fluorobenzyl Bromide; O-Fluorobenzyl Bromide

Brief Introduction

2-fluorobenzyl bromide is used as an organic intermediate.

Xylene Cyanol Ff

MSDS

CAS:4463-44-9

Molecular Formula:C25H27N2NaO7S2

Alias

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Sodium Hydrogen 4-[[4-(Ethylamino)-M-Tolyl][4-(Ethylimino)-3-Methylcyclohexa-2,5-Dien-1-Ylidene]Methyl]-6-Hydroxybenzene-1,3-Disulphonate; 5-Cyclohexadien-1-Ylidene]Methyl]-6-Hydroxy--Methyl-Monosodiumsalt

Brief Introduction

It can be used as redox indicator (orange yellow), biological staining agent, permeability measurement of tissue membrane and trace magnesium in nickel.

Tetrapropylammonium Hydroxide

MSDS

CAS:4499-86-9

Molecular Formula:C12H29NO

Alias

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1-Propanaminium,N,N,N-Tripropyl-,Hydroxide; N,N,N-Tripropyl-1-Propanaminiuhydroxide; N,N,N-Tripropyl-1-Propanaminiumhydroxide; Tetrapropyl-Ammoniuhydroxide

Brief Introduction

It is used to control pore size and synthesize zeolite in titration and preparation of Si Al catalyst.

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