Other Auxiliary Agent

Bisphenol A diallyl ether is an important intermediate in organic synthesis, which is mainly used as crosslinking agent of epoxy resin. At present, most of the methods to synthesize bisphenol A diallyl ether are to add bisphenol A and base into the solvent to form bisphenol a salt, and then add allyl halide to etherify the product. This requires the use of additional solvents. The recovery and treatment of solvents not only increases the cost, but also most of the solvents used are harmful to the environment. The prior art uses ethanol as the solvent and bisphenol A, sodium hydroxide and chloropropene as raw materials to synthesize bisphenol A diallyl ether. This method uses ethanol as solvent. Although it is relatively environmentally friendly, it is difficult to reuse ethanol due to the production of water in the reaction, and excess chloropropene will react with ethanol to produce chloropropene ether. The product synthesized by this method has deep color and needs to be washed with toluene and adsorbed with activated carbon to obtain qualified products, which virtually increases the use of solvent. In the prior art, toluene and diallyl ether are used as solvents to react allyl alcohol with bisphenol A under catalyst conditions to obtain bisphenol A diallyl ether. This method will produce many by-products and the yield is very low.

Micacin is a semi synthetic aminoglycoside antibiotic, which is obtained by introducing aminohydroxybutyryl chain into the streptomycin part of kanamycin a molecule. Its sulfate is commonly used as white or off white crystalline powder; Almost odorless and tasteless. It is very soluble in water and almost insoluble in methanol, acetone or chloroform. The antibacterial spectrum is similar to that of gentamicin. It has good antibacterial effect on Escherichia coli, Pseudomonas aeruginosa, indole negative and positive Proteus, Klebsiella, Acinetobacter, Citrobacter, Serratia and Enterobacter. Amikacin also has good antibacterial effect on Mycobacterium tuberculosis, atypical mycobacterium and Staphylococcus aureus. Other gram-positive cocci, anaerobic bacteria, Rickettsia, fungi and viral bacteria are not sensitive to this product.

This product is a permitted edible spice and can be used as food additive.

This product can be used in organic synthesis.

Terguride (INN), is a serotonin receptor antagonist and dopamine receptor agonist of the ergoline family. It is approved for and used in the treatment of hyperprolactinemia. Terguride is an oral, potent antagonist of 5-HT2B and 5-HT2A (serotonin) receptors. Serotonin stimulates the proliferation of pulmonary artery smooth muscle cells, and induces fibrosis in the wall of pulmonary arteries. Together, this causes vascular remodeling and narrowing of the pulmonary arteries. These changes result in increased vascular resistance and PAH. Due to the potential anti-proliferative and anti-fibrotic activity of terguride, this potential medicine could offer the hope of achieving reversal of pulmonary artery vascular remodeling and attenuation of disease progression. In May 2008, terguride was granted orphan drug status for the treatment of pulmonary arterial hypertension. In May 2010 Pfizer purchased worldwide rights for the drug.