Tacrolimus Active pharmaceutical Ingredient (API )

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CAS NO.： 109581-93-3

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Specification： 97% to 102% ; 98.0 % to 102.0%

Documentation：

COA

COA2

Lead Time： 1-2 weeks

Max Capacity： 180MT/Year

Pallets Packing	20'FCL		40'FCL
Pallets Packing	With	Without	With	Without
1KG/Fibre Drum	1.02 MT	1.02 MT	2 MT	1.9 MT

Product Detail

Properties

PRODUCT NAME:	TACROLIMUS
RETEST PERIOD	3 Years
STORAGE:	Store below 25°C in airtight container protected from light.
PRODUCT CODE NO.:	TR
PACK SIZE:	10 gm, 20 gm, 50 gm, 100gm, 250 gm, 500 gm, 1000 gm, 2000gm
MFG. LICENSE NO.:	G/25/2343

Properties

Tacrolimus monohydrate (FK506 monohydrate) is a macrolide compound that binds to the FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase, thereby inhibiting T lymphocyte signal transduction and IL-2 transcription. Has strong immunosuppressive properties.

CAS No.

109581-93-3

Formula

C44H71NO13

Molecular Mass

822.03300

Exact Mass

821.49300

PSA

187.59000

Logp

4.51260

IUPAC

(1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone;hydrate

Matter Classification

organic

Category

Melting Point

127-129°

Boiling Point

871.7ºC at 760 mmHg

Flash Point

481ºC

Appearance

White to Almost white powder

HS Code