(3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine;dihydrochloride is an organic synthetic intermediate and pharmaceutical intermediate. In the process of laboratory research and development and chemical and pharmaceutical research and development, it is mainly used as the intermediate of the drug substance tofatinib for the treatment of adult patients with moderate to severe rheumatoid arthritis who do not respond to methotrexate.