5-ChloroThiophene-2-Carboxylic acid [5CTA]

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CAS NO.： 24065-33-6

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Specification： 99.99%

Documentation：

MSDS

COA

Lead Time： 30-60 days

Max Capacity： 50MT/Year

Packing： 50KG/Plastic Drum

Product Detail

Properties

Product Description

Catalogue Number	C420500
Chemical Name	5-Chloro-2-thiophenecarboxylic Acid
Synonyms	2-Chloro-5-carboxythiophene; 5-Chlorothiophen-2-carboxylic acid; NSC 14776;
CAS Number	24065-33-6
Molecular Formula	C₅H₃ClO₂S
Appearance	White Solid
Melting Point	150-153°C
Molecular Weight	162.59
Storage	20°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Category	Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications	5-Chloro-2-thiophenecarboxylic Acid is a metabolite of Rivaroxaban (R538000).

Properties

2-chlorothiophene-5-carboxylic acid is a pharmaceutical intermediate, which can be used to prepare 5-chlorothiophene-2-formyl chloride, an intermediate of rivaroxaban. Rivaroxaban is a new oral anticoagulant drug, which has a long curative effect through oral absorption. It is used for the prevention and treatment of venous thrombosis, with a wide range of treatment and without routine coagulation monitoring. The world's first direct factor Xa inhibitor, developed by Bayer, was approved by the US Food and Drug Administration (FDA) in 2011.

CAS No.

24065-33-6

Formula

C5H3ClO2S

Molecular Mass

162.59400

Exact Mass

161.95400

PSA

65.54000

Logp

2.09970