Cinnamic acid
[Chemical name] β-phenylacrylic acid; 3-phenyl-2-acrylic acid
Aliases: cinnamic acid, phenylacrylic acid, benzylidene acetic acid, cinnamic acid, trans-3-Phenylacrylic acid, Cinnamic acid, 3-Phenyl-2-propenoic acid
【English name】cinnamic acid; β-phenylacrylic acid
【CAS No.】 621-82-9
【Structure or molecular formula】C9H8O2
【Relative molecular weight or atomic weight】148.17
[Specification content]: 98%
【Package】:
【Density】1.245
【Melting point (℃)】133
【Boiling point (℃)】300
[Toxic LD50 (mg/kg)] Rats take 2500 orally.
【Properties】White to light yellow powder.
[Dissolution] 1 gram can be dissolved in 2L water (25℃), dissolved in 6ml ethanol in hot water, and soluble in solvents such as benzene, glacial acetic acid, carbon disulfide, etc. in any proportion
【use】
one. The application of cinnamic acid in flavors and fragrances
1. Modulate apples and cherries, which can be used as apple flavor, cherry flavor, fruit flavor and floral flavor.
2. It can be used as aromatic mixture in soap, shampoo, washing powder and daily cosmetics.
3. It has the effect of inhibiting the formation of black tyrosinase, has a certain insulation effect on ultraviolet rays, and can make brown spots lighten or even disappear. It is one of the indispensable ingredients in advanced sunscreens.
4. Cinnamic acid itself is a kind of spice, which has a good fragrance-preserving effect. It is usually used as a raw material for flavoring to make the aroma of the main spice more refreshing and volatile. Various esters of cinnamic acid (such as A, B, C, D, etc.) can be used as a fixative for beverages, cold drinks, candy, alcohol and other foods.
two. The application of cinnamic acid in food additives
1. Cinnamic acid is used to synthesize L-phenylalanine by microbial enzymatic method. L-phenylalanine is an important food additive-the main raw material of sweet aspartame (Aspartame).
2. The United Kingdom Unilever obtained the PCTInt of the World Intellectual Property Organization. Appl. Wo01 87, 080 (2001, 11.22) This article introduces the composition of cinnamic acid and pasteurization additives, which have strong sterilization and antiseptic effects.
3. Cinnamic acid is also a component of capsaicin synthase-cinnamic acid hydrolase, which can use transgene to cultivate high-yield capsaicin varieties, which will greatly improve the quality of peppers, thereby effectively promoting the industrialization of peppers.
4. The use of cinnamic acid to prevent mildew and antiseptic sterilization can be applied to the preservation and antiseptic of grains, vegetables and fruits.
5. It can also be used in wine to make its color bright.
6. Cinnamic acid has a strong excitatory effect and can be directly added to all foods.
three. The application of cinnamic acid in the pharmaceutical industry
In the pharmaceutical industry, it can be used to synthesize the important drugs for the treatment of coronary heart disease, lactic acid, Xintongping and Xintongping, and to synthesize baclofen and cinnamon piperazine to make "Xinkean", fungicides, hemostatic drugs, etc. It can also be used to synthesize meclofenac and cinnamon piperazine to be used as a spinal bone relaxant and antispasmodic. Mainly used for cerebral thrombosis, cerebral arteriosclerosis, coronary arteriosclerosis and other diseases. It has a significant inhibitory effect on the proliferation of lung adenocarcinoma cells. Cinnamic acid is an effective inhibitor of A-5491 human lung adenocarcinoma cells and has great application value in anti-cancer. To
Four. The application of cinnamic acid in beauty
Cinnamic acid can be used in cosmetics. Tyrosinase is a key enzyme for melanin synthesis. It initiates the cascade reaction that converts tyrosine into melanin biopolymers. Cinnamic acid has the effect of inhibiting the formation of black tyrosinase. It has a certain insulating effect and can make brown spots lighten or even disappear. It is one of the essential ingredients in advanced sunscreens. The significant antioxidant effect of cinnamic acid has a good effect on slowing down the appearance of wrinkles. To
five. Application of cinnamic acid in pesticide industry
In the agricultural industry, cinnamic acid is used as a growth promoter and long-acting fungicide for the preservation of fruits and vegetables. To
six. Application of cinnamic acid in organic synthesis chemical industry
In organic chemical synthesis, cinnamic acid can be used as a slow-release agent for galvanized sheets, a heat stabilizer for polyvinyl chloride, a crosslinking agent for polycarbamates, a flame retardant for hydantoin and polycaprolactam, and a chemical analysis reagent. It is also a reagent for determining the separation of uranium and vanadium; it is also the main synthetic raw material for negative photosensitive resin. Mainly synthesize cinnamate, polyvinyl alcohol cinnamate, polyvinyloxy cinnamate, and epoxy resin whose pendant group is cinnamate. To
Used in plastics, it can be used as a heat stabilizer for PVC, a sterilization, mildew, and deodorant. It can also be added to rubber and foam to make deodorant shoes and insoles. It can also be used for cotton cloth and various synthetic fibers, leather, and coatings. , Shoe polish, straw mats and other products to prevent mildew.