Gefitinib

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Gefitinib

CAS NO.： 184475-35-2

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Specification： 99.0%

Documentation： Get COA after inquiry

Lead Time： 1-2 weeks

Max Capacity： -

Packing： 25KG/Fibre Drum

Product Detail

Properties

English name: Gefitinib

English alias: Iressa; N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine; Irressat; N-(3-chloro-4-fluorophenyl)-7- methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine; Gefitinib;

CAS number: 184475-35-2

Molecular formula: C22H24ClFN4O3

Molecular weight: 446.90200

Quality: 446.15200

PSA: 68.74000

LogP: 4.28650

Density: 1.322g/cm3

Melting point: 119-1200C

Boiling point: 586.8oC at 760 mmHg

Refractive index: 1.621

Purpose: Export of medicine, chemical industry and scientific research

Properties

Gefitinib is a quinazoline epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. It inhibits the autophosphorylation of tyrosine kinase domain in EGFR cells by competitive binding to ATP and blocks the transmission of downstream signals, so as to inhibit tumor angiogenesis, cell proliferation, invasion and metastasis and promote apoptosis.

CAS No.

184475-35-2

Formula

C22H24ClFN4O3

Molecular Mass

446.90200

Exact Mass

446.15200

PSA

68.74000

Logp

4.28650