3-Iodo-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine

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3-Iodo-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine

CAS NO.： 151266-23-8

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Properties

Properties

4-Amino-3-iodo-1H-azorrolo[3,4-D]pyrimidine can be used as a reagent for the discovery and preparation of CHMFL-FLT3-122, and can be used as an oral and effective FLT3-ITD positive acute myeloid leukemia inhibitor . Develop and prepare effective and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors, which can prevent the transmission of malaria to mosquitoes.

CAS No.

151266-23-8

Formula

C5H4IN5

Molecular Mass

261.02300

Exact Mass

260.95100

PSA

80.48000

Logp

1.12090

IUPAC

3-iodo-2H-pyrazolo[3,4-d]pyrimidin-4-amine

Matter Classification

organic

Category

Density

2.92±0.1 g/cm3

Boiling Point

312.3±52.0 °C

Flash Point

255.5ºC

Appearance

solid

Acidity and Basicity

alkalinity, reducibility

HS Code

29335990

Risk Code

R36/37/38-22

Safety Label

Xn

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