Diethyl 5-ethylpyridine-2,3-dicarboxylate is an important pharmaceutical and pesticide intermediate. For example, it can be used in the synthesis of Imazethapyr. Imazethapyr is an organic heterocyclic herbicide, which belongs to imidazolinone compounds, also known as prochloraz, imazethapyr nicotinic acid, Paclobutrazol, prochloraz and miecaoyan. Its isopropylamine salt is suitable for the control of all weeds. It has excellent herbicidal activity against Cyperaceae weeds, annual and perennial monocotyledonous weeds, broad-leaved weeds and miscellaneous trees, and can be used before or after bud, It can be quickly absorbed by plant roots and leaves, inhibit the biosynthesis of plant side chain amino acids (valine, leucine, isoleucine), destroy protein, inhibit the growth of weeds and promote their death.