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Joyang Laboratories
Joyang Laboratories
17 YRS
Jiangsu, China
Main Products:
Bacitracin Zinc / Bacitracin / Fusidic Acid / Fusidate Sodium / Cyclosporin A / Mycophenolate Mofetil / Mycophenolic Acid / Pioglitazone Hydrochloride / Capecitabine / Febuxostat
Jiangsu, China
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Mycophenolic Acid / CAS 24280-93-1
OVERVIEW
Packaging
20 KG/Fibre Drum
Lead Time
14-30 days
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DESCRIPTION
Mycophenolic Acid
1、Nomenclature
English name： Mycophenolic Acid
2、Structural formula
Molecular Structure |
|
Molecular formula：C17H20O6
Molecular weight：320.34
CAS No.：24280-93-1
3、Mechanism and clinical use:
As an intermediate of mycophenolate mofetil.
4、Packaging size specification
Inner package: double-layers polyethylene bag and aluminum foil bag.
Outer package: fiber drum
Packaging size: 20 Kg/drum
Typical Properties
Summary
Mycophenolate acid (MPA) is an active component of mycophenolate mofetil after metabolism in vivo. It is a powerful noncompetitive hypoxanthine nucleotide dehydrogenase (IMPDH) inhibitor. It can selectively inhibit the proliferation of T and B lymphocytes stimulated by mitogen and alloantigen, and inhibit the production of antibody by B lymphocytes. In addition, MPA can also block the migration of lymphocytes and monocytes to the sites of rejection and inflammation by inhibiting the glycosylation of adhesion molecules on the surface of lymphocytes and monocytes related to endothelial cell adhesion; Therefore, MPA has good antiviral, antifungal, antibacterial, antitumor and immunosuppressive activities; It is often used in the treatment of rejection of heart and kidney transplantation and immune diseases such as lupus nephritis and vasculitis.
CAS No.
24280-93-1
Formula
C17H20O6
Molecular Mass
320.33700
Exact Mass
320.12600
PSA
93.06000
Logp
2.73320
IUPAC
(E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
SMILES
CC1=C2COC(=O)C2=C(C(=C1OC)C/C=C(\C)/CCC(=O)O)O
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Synthetic Anti Infective Drugs
Chemical and Physical Properties
Melting Point
141 °C
Density
1.29 g/cm3
Boiling Point
611.6 ºC
Flash Point
225.8 ºC
Appearance
White to grayish white powder
Export information
HS Code
29322090
Export Rebate
13%
UN No.
2811
DG-Class
6.1(b)
Risk Code
22-61-40-68-50/53-48/25-52/53-36-20/21/22-11
Safety Label
Xn,N,T,F
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