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Huanggang Hengxingyuan Chemical Co., Ltd.

20 YRS

Hubei, China

CNY 2 Million

33300 m²

Less than 50 people

Main Products: Melatonine / Benserazide Hydrochloride / L-Carnitine / 3,3'-Diindolylmethane / Benfotiamine

Hubei, China

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Benserazide Hydrochloride / CAS 14919-77-8

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Benserazide hydrochloride

Structural formula：

Product Name: Benserazide hydrochloride

Molecular Formula: C₁₀H₁₅N₃O₅·HCL

Molecular Weight: 293.7

CAS#: 14919-77-8

ITEMS	STANDARDS	Result
Identification:	IR	Complies
Opticalrotation	-0.05to+o.o5	+0.02
PH	4.0to 5.0	4.2
Impurity A	≤0.5%	0.02%
Individual other impurity	≤ 0.5%	0.30%
Total impurities :	≤1.0%	0.32%
Heavy metals:	≤10ppm	Complies
Water	≤1.0%	0.4%
Sulfated ash	≤0.1%	0.070%
Assay on dry basis	98.5%— 101.5%	99.33%
CONCLUSION:ACCORD WITH EP7.0/BP2018

Typical Properties

Benserazide Hydrochloride is a peripheral decarboxylase inhibitor that is used in combination with levodopa to make a compound preparation, doserazide. Benserazide Hydrochloride, used as an AADC inhibitor in combination with levodopa, inhibits the conversion of levodopa into dopamine in the periphery, thus increasing the amount of levodopa that enters the brain and effectively improving parkinsonian symptoms.

CAS No.

14919-77-8

Formula

C10H16ClN3O5

Molecular Mass

293.70400

Exact Mass

293.07800

PSA

148.07000

Logp

0.52790

IUPAC

2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide;hydrochloride

SMILES

C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O.Cl

Matter Classification

organic

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