Heparin sodium

[ Grade ] :Injectable

[ Product capacity ] :5 million mega per year

[ Specification ] :EP/USP/BP/CP/IP

[ Packaging ] :5kgs/tin, two tins to a carton

[ introduction ] :

Heparin is a sulfated natural mucopolysaccharide, which widely exists in human and mammalian tissues and has anticoagulant effect. Heparin is produced by mast cells close to blood vessels and often exists in the form of proteoglycan units. Its chemical structure is alternately connected by D-glucuronic acid and D-glucosamine. Its molecular weight distribution is 5000 ~ 30000 and the average molecular weight is 20000;

Heparin used clinically is extracted and purified from the intestinal mucosa of healthy pigs. Sodium and calcium salts of heparin are usually used clinically, mainly heparin sodium;

Heparin has strong anticoagulant and antithrombotic functions, that is, inhibiting Xa and IIA. The anticoagulant mechanism of heparin is unique. It mainly inhibits the formation and activity of prothrombin activator and thrombin by combining with antithrombin Ⅲ (at Ⅲ), so as to promote the dissolution of fibrin (thrombus), and indirectly affect the release of coagulation factors in platelets by inhibiting the adhesion and aggregation of platelets, Therefore, it has anticoagulant effect both inside and outside the human body. In addition to its anticoagulant and antithrombotic functions, heparin also has many biological functions, such as reducing blood lipid, anti atherosclerosis, anti proliferation of middle membrane smooth muscle cells (SMC), anti inflammation, anti allergy, anti-virus, anti-cancer and so on. Therefore, heparin is widely used in medicine and has a good therapeutic effect on a variety of diseases;

In addition to being directly used in clinical anticoagulant and antithrombotic, heparin is also the raw material for the production of various heparin derived drugs such as bottom molecular heparin.