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Zhejiang Qinghe Advanced Material Technology Co.,Ltd.

7 YRS

Zhejiang, China

CNY 35 Million

79920 m²

Less than 50 people

Main Products: 2-Tetrahydrofuroic Acid

Zhejiang, China

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2-Tetrahydrofuroic Acid / CAS 16874-33-2

OVERVIEW

Packaging

200 KG/Plastic Drum

Lead Time

In Stock

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DESCRIPTION

2-Tetrahydrofuroic Acid

Basic information of 2-Tetrahydrofuroic Acid

Alias: Tetrahydro-2-Furoic Acid

CAS NO：16874-33-2

Molecular formula: C5H8O3

Molecular weight: 116.11

Appearance: colorless to light yellow liquid

Package: 200kg/ plastic barrel

Application of 2-Tetrahydrofuroic Acid

Used as pharmaceutical intermediate

Typical Properties

(R) - 2-THFC and (S) - 2-THFC can be obtained by resolution of 2-Tetrahydrofuroic Acid. Chiral 2-Tetrahydrofuroic Acid is an important ligand synthon in asymmetric synthesis. Among them, (R) - 2-THFC is an important intermediate in the synthesis of furopenem. It can be used as an antagonist of VLA-4 antigen and a chiral resolution agent of xofluza.（S) - 2-THFC is the main raw material for the preparation of chiral auxiliary (S) - acetyltetrahydrofuran, the raw material for the preparation of cephalosporin antibiotics intermediates, and the important intermediate for the preparation of hormone releasing hormone LHRH.

CAS No.

16874-33-2

Formula

C5H8O3

Molecular Mass

116.11500

Exact Mass

116.04700

PSA

46.53000

Logp

0.25000

IUPAC

oxolane-2-carboxylic acid

SMILES

CN(CC1=CC(=C(C=C1)Cl)Cl)C(=O)CN2CNC3CCC(CC3C2=O)C4CCN(CC4)C(=O)C5CCCO5

Matter Classification

organic

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