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North China Pharmaceutical Company.Ltd
North China Pharmaceutical Company.Ltd
32 YRS
Hebei, China
Main Products:
Cephradine / Potassium Benzylpenicillin / Benzathine Benzylpenicillin / Procaine Penicillin G / Phenoxymethylpenicillin Potassium / Vitamin B12 / Cephalexin / Mecobalamin / Cefoxitin Sodium Salt / Cefuroxime Sodium Salt
Hebei, China
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Cefuroxime Sodium Salt / CAS 56238-63-2
OVERVIEW
Packaging
25 KG/BOTTLE
Lead Time
14-30 days
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DESCRIPTION
Cefuroxime Sodium Salt
CAS:56238-63-2
Molecular formula：C16H15N4NaO8S
Molecular weight：446.36700
Appearance:White to almost white powder
Synopsis:Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefuroxime sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. Lack of cross-linking results in a reduction of cell wall stability and leads to cell lysis.
Structural formula:
Typical Properties
Summary
Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefuroxime sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. Lack of cross-linking results in a reduction of cell wall stability and leads to cell lysis.
CAS No.
56238-63-2
Formula
C16H15N4NaO8S
Molecular Mass
446.36700
Exact Mass
446.05100
PSA
201.89000
Logp
-0.84160
IUPAC
sodium;(6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
SMILES
CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)[O-].[Na+]
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Antibiotics
Chemical and Physical Properties
Melting Point
240-245°C(dec)
Appearance
White crystalline solid
Acidity and Basicity
neutral reducibility
Export information
HS Code
29419059
Export Rebate
13%
Export Formalities
Q
UN No.
0.0
DG-Class
0.0
Risk Code
R42/43-36/37/38-20/21/22
Safety Label
Xn
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