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Shaanxi Dasheng Pharmaceutical Tech Co., Ltd.
Shaanxi Dasheng Pharmaceutical Tech Co., Ltd.
23 YRS
Shaanxi, China
Main Products:
Topiramate / Alendronate Sodium Trihydrate / Imatinib Mesylate / Aceclofenac / Procaterol Hydrochloride Hemihydrate / Calcium Gluconate Monohydrate / Glycerol / Nitroglycerin / Chlorhexidine Diacetate / Sodium Phosphonatoformate Hexahydrate / Chlorhexidine Hydrochloride / Bicalutamide
Shaanxi, China
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Topiramate / CAS 97240-79-4
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
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DESCRIPTION
Topiramate
1. CAS RN: 97240-79-4
2. English Name：Topiramate
Synonyms:2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate; Topamax; Tracrium; Toiramate:
3.Structural Formular
4. Molecular formula & Molecular weight: C12H21NO8S 339.37
5.Appearance: It’s a white to off-white powder. Freely soluble in dichloromethane
6. Quality Standard: USP43
7. Usage: It’s a new drug of anticonvulsants.
8.Storage: It stored in sealed containers, cool and dry place, and away from light.
9. Packing: Paper bucket, 25kg/drum.
10.HS CODE: 2932 9990.99
Typical Properties
Summary
Topiramate (TPM), also known as topiramate, topivonte and topmai, is a natural monosaccharide dextro fructose sulfide. Together with non aminoester, lamotrigine and aminohexenoic acid, TPM is a broad-spectrum antiepileptic drug widely used in clinical in China. It can be used to control different types of epilepsy. Its curative effect and pharmacokinetics are good, but it can cause cognitive impairment and neurotoxicity in children and when the dosage is fast, And easy to promote kidney stones.
CAS No.
97240-79-4
Formula
C12H21NO8S
Molecular Mass
339.36200
Exact Mass
339.09900
PSA
123.92000
Logp
1.38570
IUPAC
[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-6-yl]methyl sulfamate
SMILES
CC1(O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C)C)COS(=O)(=O)N)C
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Nervous System Drugs
Chemical and Physical Properties
Melting Point
125°C
Density
1.336g/cm³
Boiling Point
438.7ºC at 760 mmHg
Flash Point
219.1ºC
Appearance
White to grayish white crystalline powder
Export information
HS Code
29350090
Export Rebate
10/13%
UN No.
0.0
DG-Class
0.0
Risk Code
R36/37/38
Safety Label
Xn
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