Tert-Butyl 7-Bromo-3,4-Dihydroisoquinoline-2(1H)-Carboxylate / CAS 258515-65-0

Highlights of TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE:

▶ Cost Leadership | Highly Competitive Pricing

Leveraging in-house large-scale production and mature, optimized synthetic processes, we offer more advantageous pricing at comparable quality levels, effectively reducing customers’ R&D and bulk procurement costs.

▶ Benchmark Quality | High Purity & Superior Performance

The product features high purity, stringent control over individual and total impurities, stable structure, and excellent reactivity, meeting the standards for pharmaceutical intermediate R&D and synthesis applications.

▶ Sufficient Capacity | Reliable Supply

Our plant is equipped with full capabilities for lab-scale, pilot-scale, and commercial-scale production. With ample inventory and fast turnaround times, we ensure reliable supply.

▶ Wide Range of Applications

• Synthetic intermediates for small-molecule pharmaceuticals

• Structural modification of heterocyclic compounds

• Starting material for Suzuki cross-coupling reactions

• Building blocks for new drug discovery and fine organic synthesis

Quick Details

Packaging & Delivery

Profile ofSuzhou ITIC Medical Chemistry Co., Ltd.

Suzhou ITIC Medical Chemistry Co., Ltd. was established in 2009 and is located in Suzhou High-tech Zone, Jiangsu Province, China. The company specializes in the R&D, production, and sales of pharmaceutical intermediates, with a strong technical advantage in heterocyclic pharmaceutical intermediates.

With a solid development history, the company has grown into a high-tech enterprise integrating R&D and production, possessing approximately 2,500 m² of R&D and manufacturing facilities. It has filed over 80 domestic and international invention patent applications and been granted more than 20 invention patents. The company is certified under ISO 9001 and ISO 14001, and has established a Suzhou Municipal Engineering Technology Research Center for Anti‑cancer Pharmaceutical Intermediates as an R&D platform.

Main business areas include:

✔Pharmaceutical intermediates:Core products cover piperazine derivatives, chiral piperidine and pyrrolidine derivatives, quinoline and tetrahydroisoquinoline derivatives, spiro compounds, and other series, totaling over 500 products. The company offers scalable production from gram to ton levels.

✔Technical services:Process design and development of molecular building blocks, process transfer and outsourcing services, process development and production technology improvement (green chemistry, cost reduction) for pharmaceutical intermediates.

The company is committed to providing better products and services to global customers, and to jointly advancing the development of the pharmaceutical chemistry field.

Why Choose Suzhou ITIC Medical Chemistry Co., Ltd.?

▶ Strong R&D Capability and Patented Technologies

Since its establishment in 2009, the company has been deeply engaged in the field of heterocyclic pharmaceutical intermediates, bringing together a professional team with years of experience in chemical synthesis and process research. It is equipped with various professional testing instruments such as NMR, HPLC, and LC-MS. The company has multiple R&D platforms including the Suzhou Municipal Engineering Technology Research Center for Anti‑cancer Pharmaceutical Intermediates. As of the end of 2021, it has been granted more than 20 invention patents, demonstrating profound technical accumulation in pharmaceutical intermediates, especially heterocyclic compounds.

▶ Strict Quality Management and System Certification

The company has obtained ISO 9001 and ISO 14001 certifications, and has passed rigorous audits from many well-known domestic and international pharmaceutical companies such as Pfizer, Merck, and Novartis. In addition, the company has received multiple national level honorary qualifications.

▶ Rich Product Portfolio and Scalable Production Capacity

The company's core products cover a wide range of categories, totaling over 500 products, with scalable production capacity from gram to ton levels. The company has long focused on the R&D, production, and custom synthesis of heterocyclic pharmaceutical intermediates such as piperidine, pyridine, pyrrolidine, and piperazine, establishing significant technical advantages and industry influence in these niche areas.

▶ Global Vision and Customer Orientation

Located in Suzhou High‑tech Zone with convenient transportation and complete supporting facilities, the company stands at the forefront of pharmaceutical R&D and large‑scale supply, striving to become a high‑quality manufacturer in the global pharmaceutical intermediate field. The company always adheres to a customer‑needs‑oriented philosophy, upholds safety, environmental protection, and sustainable development, and provides global customers with high‑quality, high‑value‑added products and services.

Introduction of tert-Butyl 7-bromo-3,4-dihydroisoquinoline-2(1H)-carboxylate (CAS 258515-65-0)

This product is a highly active pharmaceutical intermediate containing an isoquinoline skeleton, a bromine active site, and a Boc protecting group. It features good reaction selectivity and high stability. It is widely used in new drug development and organic synthesis. Through cross-coupling reactions such as Suzuki and Buchwald‑Hartwig, it can efficiently prepare various isoquinoline derivatives, serving as a core building block for candidate drug discovery in areas such as anti‑tumor and neuroprotection.

Applications of tert-Butyl 7-bromo-3,4-dihydroisoquinoline-2(1H)-carboxylate (CAS 258515-65-0)

1）Pharmaceutical intermediate: Used to construct isoquinoline and tetrahydroisoquinoline derivatives, supporting new drug screening and structural optimization.

2）Research standard: Can be used as a reference standard for HPLC and other analytical tests.

3）Others: Occasionally used as a reference material for pesticide residue testing.

Advantages of Suzhou ITIC Medical‘s tert-Butyl 7-bromo-3,4-dihydroisoquinoline-2(1H)-carboxylate (CAS 258515-65-0)

1）Purity ≥98%, with complete NMR/HPLC/GC test reports provided.

2）White crystalline solid, soluble in common organic solvents.

3）Strict impurity control, moisture ≤0.5%.

4）The company has a 2,500 m² R&D center and more than 20 granted invention patents, with extensive experience in the field of heterocyclic intermediates.

Keywords Related to Octocrylene CAS 6197304

TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE; CAS 258515-65-0; 98% TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE; Pharmaceutical Grade TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE; TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE Stock Solution; China TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE; TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE Manufacturer; TERT-BUTYL 7-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE Supplier；N-Boc-7-bromo-THIQ

FAQ of Suzhou ITIC Medical Chemistry Co., Ltd.

Q1. Are you a manufacturer or a trading company?

We are a professional manufacturing enterprise dedicated to the R&D, production, and sales of heterocyclic building blocks and pharmaceutical intermediates, with a focus on chiral and protected building blocks such as the Boc-protected pyrrolidine series. We have our own R&D center and complete testing equipment.

Q2. What main products and business scopes does your company cover?

Core Products：

1）1‑Boc‑3‑pyrrolidinone (101385‑93‑7)

2）1‑Boc‑3‑methylenepyrrolidine (114214‑71‑0)

3）1‑Boc‑3‑(hydroxymethyl)pyrrolidine (114214‑69‑6)

4）(S)‑1‑Boc‑3‑(hydroxymethyl)pyrrolidine (199174‑24‑8)

5）(R)‑1‑Boc‑3‑(hydroxymethyl)pyrrolidine (138108‑72‑2)

6）1‑Boc‑3‑pyrrolidinecarboxaldehyde (59379‑02‑1)

7）1‑Boc‑3‑pyrrolidinecarboxylic acid (59378‑75‑5)

8）(S)‑1‑Boc‑3‑pyrrolidinecarboxylic acid (140148‑70‑5)

9）(R)‑1‑Boc‑3‑pyrrolidinecarboxylic acid (72925‑16‑7)

Q3. We don’t know you at all, how can we trust you?

We have obtained ISO quality system certification, hold a number of patented technologies, and our products are supported by multiple technical certifications including COA. We are people-oriented and committed to providing excellent service.

Q4. How to contact you for business consultation and sample application?

You can contact us through our Chemball official page, email, mobile phone, or any way you like! Our professional sales team will try our best to respond to your inquiries as soon as possible and provide professional product solutions.

Q5. Can you provide customized synthesis services for products?

Yes, we have a 3000 square meter professional R&D center with a strong R&D team, and we can undertake customized synthesis services for various pharmaceutical raw materials and intermediates according to your technical requirements and samples.