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Sichuan Deebio Pharmaceutical Co.,Ltd.

29 YRS

Sichuan, China

CNY 50 Million

83250 m²

100-500 people

Main Products: Pepsin / Kallidinogenase / Elastase / Cytochrome C Solution / Heparin Sodium / Gastric Mucin / Chondroitin Sulfate / Chondroitin Sulfate Sodium

Sichuan, China

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Chondroitin Sulfate / CAS 9007-28-7

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Chondroitin Sulfate

CAS NO. :9007-28-7	Pharmacopoeia standard ：CP
HS CODE :3001.9090.99	File service ：Chinese GMP/ DMF / EU-DMF

Source：Porcinecartilagetissues such asthroatbone, nasal bone, trachea.

Characters：White oryellowish powder, saltish, odourless,hygroscopic.

Process：Chondroitin Sulfate (Injection)is extracted from healthyporcinecartilagetissues.

Test Items		CP
Characters		White or yellowish powder, saltish, odourless, hygroscopic
Identification		Produce cuprous oxide red precipitation: Conforms
		Blue and purple spots: Conforms
		Sulfate: Conforms
Tests	pH	6.0～7.0（5%）
	Clarity and color	Clear（5%）
	Nitrogen	2.5%～3.5%（dry substance）
	Chloride	≤ 0.6%
	Loss on drying	≤ 10.0%（105℃, dry, 4h）
	Absorbance	A260≤ 0.28；A280≤ 0.18
	Loss on drying	≤ 20ppm
	Molecular weight and distribution	MW: 35000～50000, Mw/Mn < 1.8
Content		Hexosamine counted as glucosamine≥30.0%(dry substance)
Microbial Impurities	TAMC	≤ 1000cfu/g
	TYMC	≤ 100cfu/g
	E.coli	Conforms
	Salmonella	Conforms

Typical Properties

Chondroitin sulfate (CS) is a kind of glycosaminoglycans covalently linked to proteins to form proteoglycans. Chondroitin sulfate is widely distributed in the extracellular matrix and cell surface of animal tissues. The sugar chain is polymerized by alternating glucuronic acid and N-acetylgalactosamine, and connected to the serine residue of core protein through a sugar like link region. Although the main chain structure of polysaccharide is not complex, it shows a high degree of heterogeneity in terms of the degree of sulfation, sulfate group and the distribution of the two differences to the re chain of isouronic acid. The fine structure of chondroitin sulfate determines the functional specificity and interaction with a variety of protein molecules.

CAS No.

9007-28-7

Formula

C13H21NO15S

Molecular Mass

463.36854

Exact Mass

479.05800

PSA

287.45000

Logp

-3.73080

IUPAC

(2S,3S,4S,5R,6R)-6-[(2R,3R,4R,5R,6R)-3-acetamido-2,5-dihydroxy-6-sulfooxyoxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid

SMILES

CC(=O)NC1C(C(C(OC1O)OS(=O)(=O)O)O)OC2C(C(C(C(O2)C(=O)O)O)O)O

Matter Classification

organic

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