Dexamethasone Sodium Phosphate

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CAS NO.： 2392-39-4

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Specification： 98.5%

Documentation：

COA

Lead Time： In Stock

Max Capacity： -

Packing： 25KG/Fibre Drum

Product Detail

Properties

Dexamethasone sodium phosphate
CAS No	2392-39-4	Molecular formula	C22H28FNa2O8P
Molecular weight	516.405	Precision mass	516.13
LogP	2.8891	PSA	156.83
Appearance and traits	White to off white powder

Properties

Dexamethasone sodium phosphate belongs to adrenocortical hormone drugs, which can stabilize lysosomal membrane and reduce the release of lysosomal hydrolase; It can inhibit the production of bradykinin, 5-hydroxytryptamine and prostaglandin, increase the stability of mast cell granules and reduce the release of histamine; Therefore, it has anti-inflammatory effect. It can exert immunosuppressive effect by inhibiting the function of macrophages. It can inhibit the formation of fibroblasts, prevent corneal scar, reduce scar formation and protect vision when used in trauma. It can inhibit or reduce the formation of neovascularization in corneal and conjunctival diseases. Local application can reduce rejection and scar formation in corneal transplantation and myopic surgery. It is used in the treatment of autoimmune diseases, allergy, inflammation, rheumatism, asthma, ophthalmology and dermatology.

CAS No.

2392-39-4

Formula

C22H28FNa2O8P

Molecular Mass

516.40500

Exact Mass

516.13000

PSA

156.83000

Logp

2.88910

IUPAC

disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate

Matter Classification

organic

Category

Melting Point

233-235 °C

Density

1.32 g/cm3

Boiling Point

669.6 ºC

Flash Point

358.7 ºC

Appearance