English Name: Olaparib
CAS No.: 763113-22-0
Molecular formula: C24H23FN4O3
Molecular weight: 434.46
EINECS No.: 642-941-5
Density: 1.43
Uses: olapani is a novel inhibitor of poly ADP ribose polymerase (PARP), including PARP1, PARP2, and parp3. PARP mediates a DNA repair mechanism, which plays an important role in DNA damage repair and apoptosis. Therefore, Ola Pani's specific DNA damage repair mechanism for targeted cells plays an important role in attacking the key loopholes in BRCA1 and BRCA2 mutant cancer cells, and can be used in the mutation of the breast cancer susceptibility gene (BRCA). Maintenance therapy for patients with recurrent severe ovarian cancer sensitive to platinum drugs.