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Tavaborole

CAS NO.： 174671-46-6

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Specification： 99.0%

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Lead Time： 14-30 days

Max Capacity： -

Packing： 25KG/Fibre Drum

Product Detail

Properties

Tavaborole

Product introduction:

Tavaborole exerts his antifungal activity by forming adducts with cytoplasmic leucylaminotransferase (tRNA) synthase to prevent cell protein synthesis. Effective treatment of onychomycosis.

CAS：174671-46-6

Molecular formula: C₇H₆BFO₂

Molecular weight: 151.93

Structural type:

Chemical property: white to beige solid

Product purpose: An antifungal agent that can resist Trichophyton and effectively treat onychomycosis.

Properties

Tavaborole (AN2690, trade name Kerydin) is a topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed. Tavaborole began its Phase 3 trials in December 2010 and was approved in July 2014. Tavaborole inhibits an essential fungal enzyme, leucyl-tRNA synthetase, that is required for protein synthesis. The inhibition of protein synthesis leads to termination of cell growth and then cell death, eliminating the fungal infection.

CAS No.

174671-46-6

Formula

C7H6BFO2

Molecular Mass

151.93100

Exact Mass

152.04400

PSA

29.46000

Logp

0.04340

IUPAC

5-fluoro-1-hydroxy-3H-2,1-benzoxaborole

Matter Classification

organic

Category

Melting Point

120-122℃

Density

1.288 g/cm3

Boiling Point

230.831ºC

Appearance

white to beige powder

Acidity and Basicity

acidness

HS Code

29349990

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