Haloperidol
Synonymous: 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-4-hydroxypiperidinium
CAS: 52-86-8
Structure:
Molecular formula: C21H23ClFNO2
Molecular weight: 375.87
Authentication code:  H37022198
Specification: China Pharmacopoeia 2010
Appearance: White or almost white crystalline powder
Melting point: 149-153οC
Absorption coefficient: 338-360
Individual biggest impurity: ≤0.5%
Total impurities: ≤ 1.0%
Loss on drying: Not more than 0.5% (Vacuum at 60οC)
Residue on ignition: Not more than 0.1%
Assay: Not more than 98.5%
Application: Used for curing psychopathy, schizophrenia, and madness disease.
    
   
  
    
    
  
  
  
    
    
    This product is the most commonly used drug in butyryl benzene antipsychotics and is listed in the national catalogue of essential drugs. Antipsychotics, formerly known as strong tranquilizers, are mainly used to control schizophrenia and other diseases related to hallucinations, delusions, excitement, impulses and so on. Haloperidol is mainly used to resist mania and hallucinations in acute and chronic schizophrenia. It has a significant effect on controlling excitement and agitation, but it has no effect on depression and indifference in schizophrenia. The oral LD50 of rats was 165 mg / kg.
    
    
      
        
          
          
          
        
      
        
          
          
          
        
      
        
          
          
          
        
      
        
          
          
          
        
      
        
          
          
          
        
      
        
          
          
          
        
      
        
          
          
          
            IUPAC
            4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
           
        
      
        
      
     
   
  
  
  
    
    
    
      
        
      
        
      
        
          
          
          
            Matter Classification
            organic
           
          
        
      
        
          
          
          
        
      
     
   
  
  
  
    
    
    
      
        
          
          
          
        
      
        
          
          
          
        
      
        
          
          
          
        
      
        
      
        
          
          
          
            Appearance
            White or off white crystalline powder
           
        
      
        
          
          
          
            Acidity and Basicity
            
              
              
                
              
              
                neutral
              
            
           
          
        
      
     
   
  
  
  
    
    
    
      
        
          
          
          
        
      
        
      
        
          
          
          
        
      
        
          
          
          
        
      
        
          
          
          
            Risk Code
            R60-61-25-36/37/38-43-39/23/24/25-23/24/25-11