Chloramphenicol

Synonymous: levamycin

Chemical formula: C₁₁H₁₂Cl₂N₂O₅

Molecular weight: 323.14

CAS ： 56-75-7

EINECS No.: 200-287-4

Melting Point; 148 to 150 ℃

Boiling Point: 563.2 ℃

Water solubility: slightly soluble

Dense Degree: 1.474 g / cm ³

Appearance： white to off white crystalline powder

Flash Point: 294.4 ℃

Category: bacteriostatic broad-spectrum antibiotics

Malpractice End: serious adverse reactions in hematopoietic system

Uses: block protein synthesis

Product introduction:

Chloramphenicol is an antibiotic K .It is easily soluble in methanol, ethanol, propanol and ethyl acetate y, slightly soluble in ether and chloroform, and insoluble in petroleum ether and benzene. Chloramphenicol is extremely stable, and its aqueous solution will not fail after boiling for 5h. Because there are two asymmetric carbon atoms in chloramphenicol molecule, chloramphenicol has four optical isomers, of which only the left-handed isomer has antibacterial ability.

Properties

Chloramphenicol is a broad spectrum antibiotic introduced into clinical practice in 1948, but which was subsequently shown to cause serious and fatal aplastic anemia and is now used rarely and reserved for severe, life-threatening infections for which other antibiotics are not available. Chloramphenicol has also been linked to cases of acute, clinically apparent liver injury with jaundice, largely in association with aplastic anemia.

CAS No.

56-75-7

Formula

C11H12Cl2N2O5

Molecular Mass

323.12900

Exact Mass

322.01200

PSA

115.38000

Logp

1.82310