This product belongs to 8-aminoquinoline derivatives. It has strong killing effect on the infrared phase and gametophyte of Plasmodium. It is an effective drug to prevent recurrence and interrupt transmission. The antimalarial mechanism may be the interference of DNA synthesis of Plasmodium. Plasmodium must provide some enzymes or coenzymes for pentose phosphate pathway metabolism in the infrared phase by human liver cells. Due to the hydroxylation of primaquine, a large number of hydrogen donors from liver cells are consumed, resulting in the lack of enzymes or coenzymes used by Plasmodium, resulting in the death of Plasmodium in the infrared phase. This product can kill Plasmodium vivax, Plasmodium vivax, Plasmodium falciparum and Plasmodium ovale in the infrared phase schizonts. The best effect is to kill Plasmodium vivax. It can also kill gametophytes of various Plasmodium species. It has the strongest effect on Plasmodium falciparum, but has very weak effect on erythrocytic schizonts.