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Shandong Boyuan Pharmaceutical Co.,Ltd.

19 YRS

Shandong, China

CNY 60 Million

199800 m²

100-500 people

Main Products: 3,3-Dimethyl-1-Butyne

Shandong, China

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Tert-Butyl 4-(6-((6-Bromo-8-Cyclopentyl-5-Methyl-7-oxo-7,8-Dihydropyrido[2,3-d]Pyrimidin-2-yl)Amino)Pyridin-3-yl)Piperazine-1-Carboxylate / CAS 571188-82-4

99%

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Packaging

Pallets Packing	20'FCL		40'FCL
Pallets Packing	With	Without	With	Without
25 KG/Fibre Drum 99%	6.5 MT	6.8 MT	13 MT	6.8 MT

Lead Time

In Stock

Max Capacity

2 MT/Year

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DESCRIPTION

OVERVIEW

Product information:

English Name: 4-[6-[(6-bromo-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl) amino]-3-pyridinyl]-1-piperazinecarboxylic acid 1,1-dimethyl ester

Structural formula:

Molecular formula: c27h34brn7o3

Molecular weight: 584.51

CAS No.: 571188-82-4

Purity: >99%

Properties: light yellow to brown powder

Quality standard: enterprise standard

Package: 1kg; 10kg; 25kg; 100kg barrel

Application: antitumor pharmaceutical intermediate, scientific research and export

Typical Properties

Tert-butyl 4-(6-((6-bromo-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate is an impurity of Pabucilib, an experimental drug developed by Pfizer to treat breast cancer. It is a selective inhibitor of cyclin dependent kinases CDK4 and CDK6. In addition, it is derived from 6-bromo-2-chloro-8 cyclopentyl-5-methylpyridine [2,3-d] pyrimidin-7 (8H) - one, used to prepare pyridine [2,3-d] pyrimidin-7 (8H) - one derivatives as CDK4 and/or CDK6 inhibitors for the treatment of diseases.

CAS No.

571188-82-4

Formula

C27H34BrN7O3

Molecular Mass

584.50800

Exact Mass

583.19100

PSA

105.48000

Logp

5.24910

IUPAC

tert-butyl 4-[6-[(6-bromo-8-cyclopentyl-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylate

SMILES

CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCN(CC4)C(=O)OC(C)(C)C)C5CCCC5)Br

Matter Classification

organic

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Tert-Butyl 4-(6-((6-Bromo-8-Cyclopentyl-5-Methyl-7-oxo-7,8-Dihydropyrido[2,3-d]Pyrimidin-2-yl)Amino)Pyridin-3-yl)Piperazine-1-Carboxylate / CAS 571188-82-4

OVERVIEW

Packaging

Lead Time

Max Capacity

REQUEST A QUOTATION

DESCRIPTION

Typical Properties

GET SAMPLE