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Sofosbuvir

Sofosbuvir / CAS : 1190307-88-0

Appearance White to almost white crystalline solid UN -
HS 29349990 DG Class -
Synonyms Propan-2-Yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-Dioxopyrimidin-1-Yl)-4-Fluoro-3-Hydroxy-4-Methyloxolan-2-Yl]Methoxy-Phenoxyphosphoryl]Amino]Propanoate; Gs-7977; (S)-2-{(S)-[(2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-Dihydro-2H-Pyrimidin-1-Yl)-4-Fluoro-3-Hydroxy-4-Methyltetrahydrofuran-2-Ylmethoxy](Phenoxy)Phosphorylamino}Propionic Acid Isopropyl Ester; (S)-Isopropyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)-4-Fluoro-3-Hydroxy-4-Methyltetrahydrofuran-2-Yl)Methoxy)(Phenoxy)Phosphoryl)Amino)Propanoate; Psi-7977 Discontinued; L-Alanine, N-[[P(S),2'R]-2'-Deoxy-2'-Fluoro-2'-Methyl-P-Phenyl-5'-Uridylyl]-, 1-Methylethyl Ester; Sophy Bouvet; Isopropyl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-Dihydro-1(2H)-Pyrimidinyl)-4-Fluoro-3-Hydroxy-4-Methyltetrahydro-2-Furanyl]Methoxy}(Phenoxy)Phosphoryl]Amino}Propanoate; Psi-7977
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Properties

Summary

Formula
C22H29FN3O9P
Molecular Mass
529.45300
Exact Mass
529.16300
PSA
167.99000
Logp
2.04740
IUPAC
propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
SMILES
CC(C)OC(=O)C(C)NP(=O)(OCC1C(C(C(O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3

Attribute classification

Matter Classification
organic
Category
API & Intermediate > Synthetic Anti Infective Drugs

Chemical and Physical Properties

Density
1.41 g/cm3
Appearance
White to almost white crystalline solid
Acidity and Basicity
alkalinity

Export information

HS Code
29349990
Export Rebate
10%

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