Linaelotide Acetate
Linaelotide Acetate / CAS : 851199-59-2
Appearance | White to off white amorphous powder; Slightly soluble in water and sodium chloride aqueous solution (0.9%). | UN | 0 |
HS | 30025100 | DG Class | 0 |
Synonyms | Argpessin; Linzess; Linacllotide; Linaelotide; Cy-14; Liclotide; L-Tyrosine, L-Cysteinyl-L-Cysteinyl-L-α-Glutamyl-L-Tyrosyl-L-Cysteinyl-L-Cysteinyl-L-Asparaginyl-L-Prolyl-L-Alanyl-L-Cysteinyl-L-Threonylglycyl-L-Cysteinyl-, Cyclic (1→6),(2→10),(5→13)-tris(Disulfide); Linaclotide Acetate; Linaclotide |

- Email: jim.yu@mail.chemball.com
- Whatsapp: 0086-18334372322
- Tel: 0086-571-8627 3270
latest price
Overview
Benefits
High Quality: Linaclotide is produced by the biosynthesis process, without residual solvent, and with high purity.
Strong supply capacity: Compared with chemical synthesis, the production capacity of the biological synthesis process is not limited. The capacity of each batch can reach the kilogram level.
The lower price: The price of Linaclotide is 5%~10% lower than that of our competitors.
Specification
Test | Specification | Result |
Appearance | White or almost white powder | white powder |
Molecular | 1526.8±1 | 1527.35 |
Purity(HPLC) | ≥98.0% | Conforms |
Related substances(HPLC) | Total impurities:≤2.0% | Conforms |
Maximum single impurity:≤1.0% | Conforms | |
Water Content(Karl Fischer) | ≤8.0% | Conforms |
Acetonitrile | NTM 410 ppm | Conforms |
Acetate (HPLC) | NMT 5.0% | Conforms |
Host Cell Protein | ≤0.01% | Conforms |
Host Cell DNA | ≤10.0 ng/mg | Conforms |
Uses
Linaclotide, also known as Linaelotide acetate under the trade name Linzess, is a 14 amino acid synthetic peptide structurally related to the endogenous guanosine peptide family and is the only FDA-approved GC-C (guanylate cyclase-C) agonist class of drugs with local onset in the gut that can be used clinically to treat adult patients with constipation-predominant irritable bowel syndrome (IBS-C) and chronic idiopathic constipation (CIC).
Picture
Properties
Summary
Attribute classification
API & Intermediate > Digestive System Drugs