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Flucytosine
Flucytosine / CAS : 2022-85-7
| Appearance | White crystalline solid | UN | - |
| HS | 29335990 | DG Class | - |
| Synonyms | 5-Fluorocytosine; 4-Amino-5-Fluoro-2(1H)-Pyrimidinone,5-Fluorocytosine,Flucytosine; 4-Amino-5-Fluoro-1,2-Dihydropyrimidin-2-One; 4-Amino-5-Fluoro-2(1H)-Pyrimidinone,Flucytosine; 4-Amino-5-Fluoro-2-Pyrimidone; Fluocytosine; Ancotil; 5-Fluorocytosin; Fluorcytosine; 6-Amino-5-Fluoro-1H-Pyrimidin-2-One; Flucytosin; 5-Fluorocystosine; 4-Amino-5-Fluoro-2-Hydroxypyrimidine; 4-Amino-5-Fluoro-2(1H)-Pyrimidinone; Ancobon; Fluorocytosine | ||
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latest price
1/6
Packing:
25 KG/Fibre Drum
ISO9001, EHS, Audit, HALAL, KOSHER
Xinxiang Tuoxin Pharmaceutical Co.,Ltd.
Henan, China
Overview
Benefits
Complete qualifications: multiple raw materials have passed GMP certification; DMF registration in India and Uzbekistan; EU REACH, HALAL, and KOSHER clean food certification.
Stable quality: The company has passed the ISO9001 certification, achieving full process control from product design and development, raw material procurement, process control to product sales.
Strong R&D strength: The company attaches great importance to investing in product development and improving its overall R&D strength.
Specification
Items | Requirements |
Description | White or almost white crystalline powder. |
Identification | 1. Fade when adding bromine liquid |
2. Max absorption at 286nm; absorbance of about 0.71 | |
3. The infrared absorption spectrum is concordant with the reference standard | |
Clarity and color | Clear and colorless |
Acidity and alkalinity | 5.5~7.5 |
Loss on drying | ≤0.5% |
Residue on ignition | ≤0.2% |
Heavy Metals | ≤0.002% |
Assay(HCLO4) | ≥98.5% |
Related impurities | Fluorouracil≤0.2% |
Other impurity≤1.0% |
Uses
Antifungal drugs: 5-fluorocytosine can be used as an antifungal drug, especially with antibacterial activity against some fungal infections. It is often used to treat infectious diseases caused by fungi such as Candida and Cryptococcus.
Conversion to antitumor drugs: 5-fluorocytosine can be metabolized into 5-fluorouracil (5-FU), which is a commonly used antitumor drug. In vivo, after 5-fluorocytosine is converted into 5-FU, it can exert antitumor activity by affecting nucleic acid synthesis, inhibiting tumor cell proliferation and inducing apoptosis.
Picture
Properties
Summary
Formula
C4H4FN3O
Molecular Mass
129.09200
Exact Mass
129.03400
PSA
71.77000
Logp
0.07240
IUPAC
6-amino-5-fluoro-1H-pyrimidin-2-one
SMILES
C1=NC(=O)NC(=C1F)N
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Synthetic Anti Infective Drugs
Chemical and Physical Properties
Melting Point
298-300 °C
Density
1.73g/cm3
Boiling Point
298ºC
Appearance
White crystalline solid
Export information
HS Code
29335990
Export Rebate
13%
Risk Code
R40-36/37/38-63
Safety Label
Xn,T,Xi
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