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Amlodipine

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Amlodipine / CAS : 88150-42-9

Appearance Almost white crystal powder UN 0
HS 29420000 DG Class 6.1
Synonyms Norvasc; Lipinox; Amlodis; 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-3-Ethoxycarbonyl-5-Methoxycarbonyl-6-Methyl-1,4-Dihydropyridine; Amlodipino; 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-1,4-Dihydro-6-Methyl-3,5-Pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester; 3-Ethyl 5-Methyl ()-2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-1,4-Dihydro-6-Methyl-3,5-Pyridine Dicarboxylate; Istin; (R,S)-2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-3-Ethoxycarbonyl-5-Methoxycarbonyl-6-Methyl-1,4-Dihydropyridine; Amlodipinum [Latin]; Amlodipinum; Amlocard; 3-Ethyl-5-Methyl-(4Rs)-2-[(2-Aminoethoxy)-Methyl]-4-(2-Chlorophenyl)-6-Methyl-1,4-Dihydropyridine-3,5-Carboxylate Benzene Sulphonate; Coroval; 3,5-Pyridinedicarboxylicacid,1,4-Dihydro-2-((2-Aminoethoxy)Methyl)-4-(2-Chlor; Amlodipine Base (Crystalline); (R)-3-Ethyl 5-Methyl 2; 3-Ethyl5-Methylester; Lotrel; Methyl Ethyl 2-(2-Aminoethoxymethyl)-4-(2-Chlorophenyl)-6-Methyl-1,4-Dihydropyridine-3,5-Dicarboxylate; Amlodipine Base
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Properties

Summary

Formula
C20H25ClN2O5
Molecular Mass
408.87600
Exact Mass
408.14500
PSA
99.88000
Logp
3.29540
IUPAC
3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
SMILES
CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN

Attribute classification

Matter Classification
organic
Category
API & Intermediate > Other Chemical Drugs
API & Intermediate > Circulatory System Drugs

Chemical and Physical Properties

Melting Point
178-179ºC
Density
1.227±0.06 g/cm3(Predicted)
Boiling Point
527.2±50.0 °C(Predicted)
Appearance
Almost white crystal powder

Export information

HS Code
29420000
Export Rebate
13%
UN No.
0
DG-Class
6.1

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